Tide Quencher™ 7.1 CPG [TQ7.1 CPG] *500 Å*
Ordering information
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Additional ordering information
Telephone | 1-800-990-8053 |
Fax | 1-800-609-2943 |
sales@aatbio.com | |
International | See distributors |
Bulk request | Inquire |
Custom size | Inquire |
Shipping | Standard overnight for United States, inquire for international |
Physical properties
Solvent | MeCN |
Spectral properties
Correction Factor (260 nm) | 0.229 |
Correction Factor (280 nm) | 0.193 |
Extinction coefficient (cm -1 M -1) | 75,0001 |
Storage, safety and handling
H-phrase | H303, H313, H333 |
Hazard symbol | XN |
Intended use | Research Use Only (RUO) |
R-phrase | R20, R21, R22 |
Storage | Freeze (< -15 °C); Minimize light exposure |
Alternative formats
Tide Quencher™ 7.1 CPG [TQ7.1 CPG] *1000 Å* |
Related products
Overview | SDSProtocol |
See also: Tide Quencher Dyes
Correction Factor (260 nm) 0.229 | Correction Factor (280 nm) 0.193 | Extinction coefficient (cm -1 M -1) 75,0001 |
Tide Quencher™ 7.1 (TQ7.1) is a non-fluorescent molecule designed to efficiently quench the fluorescence of common NIR fluorophores such as Cy7, Alexa Fluor® 700, Alexa Fluor® 750, iFluor® 700, iFluor® 710, iFluor® 720 and iFluor® 750. It is an improved version of TQ7 and BHQ3. TQ7.1 is designed to be a superior quencher with (a). much stronger absorption, and (b). much higher quenching efficiency for NIR dyes. Tide Quencher™ 7.1 CPG is an excellent building block for preparing TQ7.1-labeled oligonucleotides. The oligo prepared from (TQ7.1 CPG) may be deprotected in 0.05M potassium carbonate in methanol for 4 hours at room temperature for 2 hours. Alternatively, the oligo may be deprotected in ammonium hydroxide at room temperature for 24-36 hours. It can be used in techniques such as polymerase chain reaction (PCR), real-time PCR, and DNA sequencing. In these applications, fluorescence signals are used to monitor the amplification or detection of specific DNA sequences. TQ7.1 quenches the fluorescent signal until a specific event (like DNA strand separation or primer extension) occurs, leading to an increase in fluorescence that can be detected and quantified.
Spectrum
Open in Advanced Spectrum Viewer
Spectral properties
Correction Factor (260 nm) | 0.229 |
Correction Factor (280 nm) | 0.193 |
Extinction coefficient (cm -1 M -1) | 75,0001 |
Images
References
View all 17 references: Citation Explorer
Cooperatively enhanced photothermal-chemotherapy via simultaneously downregulating HSPs and promoting DNA alkylation in cancer cells.
Authors: Zou, Yang and Huang, Daipeng and He, Shan and Song, Xuefang and Liu, Weijian and Sun, Wen and Du, Jianjun and Fan, Jiangli and Peng, Xiaojun
Journal: Chemical science (2023): 1010-1017
Authors: Zou, Yang and Huang, Daipeng and He, Shan and Song, Xuefang and Liu, Weijian and Sun, Wen and Du, Jianjun and Fan, Jiangli and Peng, Xiaojun
Journal: Chemical science (2023): 1010-1017
Accurate identification of kidney injury progression via a fluorescent biosensor array.
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Journal: Mikrochimica acta (2022): 304
Hydroxyapatite nanoparticles promote mitochondrial-based pyroptosis via activating calcium homeostasis and redox imbalance in vascular smooth muscle cells.
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Journal: Nanotechnology (2022)
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Journal: Nanotechnology (2022)
Near-infrared/pH dual-responsive nanocomplexes for targeted imaging and chemo/gene/photothermal tri-therapies of non-small cell lung cancer.
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Journal: Acta biomaterialia (2020): 242-259
Near-Infrared Dual-Emission Ratiometric Fluorescence Imaging Nanoprobe for Real-Time Tracing the Generation of Endogenous Peroxynitrite in Single Living Cells and In Vivo.
Authors: Lin, Pengxiang and Chen, Dongxia and Zhang, Liangliang and Xu, Jiayao and Huang, Yong and Zhao, Shulin
Journal: ACS omega (2020): 13278-13286
Authors: Lin, Pengxiang and Chen, Dongxia and Zhang, Liangliang and Xu, Jiayao and Huang, Yong and Zhao, Shulin
Journal: ACS omega (2020): 13278-13286
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Journal: Biosensors (2020)
Authors: Son, Heyjin and Mo, Woori and Park, Jaeil and Lee, Joong-Wook and Lee, Sanghwa
Journal: Biosensors (2020)
In vitro isolation of small-molecule-binding aptamers with intrinsic dye-displacement functionality.
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Journal: Nucleic acids research (2018): e43
Programmed Synthesis by Stimuli-Responsive DNAzyme-Modified Mesoporous SiO2 Nanoparticles.
Authors: Balogh, Dora and Aleman Garcia, Miguel Angel and Albada, H Bauke and Willner, Itamar
Journal: Angewandte Chemie (International ed. in English) (2015): 11652-6
Authors: Balogh, Dora and Aleman Garcia, Miguel Angel and Albada, H Bauke and Willner, Itamar
Journal: Angewandte Chemie (International ed. in English) (2015): 11652-6
Ternary complexes with core-shell bilayer for double level targeted gene delivery: in vitro and in vivo evaluation.
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Journal: Pharmaceutical research (2013): 1215-27
Authors: Fan, Ying and Yao, Jing and Du, Ronghui and Hou, Lin and Zhou, Jianping and Lu, Yun and Meng, Qinggang and Zhang, Qiang
Journal: Pharmaceutical research (2013): 1215-27
Achieving effective terminal exciton delivery in quantum dot antenna-sensitized multistep DNA photonic wires.
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Journal: ACS nano (2013): 7101-18