Tide Quencher™ 7.1WS amine [TQ7.1WS amine]
Ordering information
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Additional ordering information
Telephone | 1-800-990-8053 |
Fax | 1-800-609-2943 |
sales@aatbio.com | |
International | See distributors |
Bulk request | Inquire |
Custom size | Inquire |
Shipping | Standard overnight for United States, inquire for international |
Physical properties
Molecular weight | 1134.14 |
Solvent | DMSO |
Storage, safety and handling
H-phrase | H303, H313, H333 |
Hazard symbol | XN |
Intended use | Research Use Only (RUO) |
R-phrase | R20, R21, R22 |
Storage | Freeze (< -15 °C); Minimize light exposure |
Alternative formats
Tide Quencher™ 7.1WS maleimide [TQ7.1WS maleimide] |
Tide Quencher™ 7.1WS acid [TQ7.1WS acid] |
Tide Quencher™ 7.1WS azide [TQ7.1WS azide] |
Tide Quencher™ 7.1WS alkyne [TQ7.1WS alkyne] |
Related products
Overview | ![]() ![]() |
See also: Tide Quencher Dyes
Molecular weight 1134.14 |
Tide Quencher™ 7.1WS (TQ7.1WS) is a non-fluorescent molecule designed to efficiently quench the fluorescence of common NIR fluorophores such as Cy7, Alexa Fluor® 700, Alexa Fluor® 750, iFluor® 700, iFluor® 710, iFluor® 720 and iFluor® 750. It is an improved version of TQ7 and BHQ3. TQ7.1WS is designed to be a superior quencher with (a). much stronger absorption, and (b). much higher quenching efficiency for NIR dyes. Tide Quencher™ 7.1WS amine is primarily used for labeling biomolecules that contain a carbonyl group. It can be used in techniques such as polymerase chain reaction (PCR), real-time PCR, and DNA sequencing. In these applications, fluorescence signals are used to monitor the amplification or detection of specific DNA sequences. TQ7.1WS quenches the fluorescent signal until a specific event (like DNA strand separation or primer extension) occurs, leading to an increase in fluorescence that can be detected and quantified. Fluorescence resonance energy transfer (FRET)-based assays are widely used to detect and measure the presence of specific molecules in a sample. They involve the use of a fluorescent molecule (fluorophore) and a quencher molecule such as TQ7.1WS. The fluorophore emits light when excited by a specific wavelength of light, while the quencher molecule absorbs this emitted light, effectively "quenching" the fluorescence signal.
Calculators
Common stock solution preparation
Table 1. Volume of DMSO needed to reconstitute specific mass of Tide Quencher™ 7.1WS amine [TQ7.1WS amine] to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.
0.1 mg | 0.5 mg | 1 mg | 5 mg | 10 mg | |
1 mM | 88.173 µL | 440.863 µL | 881.725 µL | 4.409 mL | 8.817 mL |
5 mM | 17.635 µL | 88.173 µL | 176.345 µL | 881.725 µL | 1.763 mL |
10 mM | 8.817 µL | 44.086 µL | 88.173 µL | 440.863 µL | 881.725 µL |
Molarity calculator
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References
View all 13 references: Citation Explorer
A Selenium-Substituted Heptamethine Cyanine Photosensitizer for Near-Infrared Photodynamic Therapy.
Authors: Sun, Jinghan and Feng, Erting and Shao, Yutong and Lv, Fangyuan and Wu, Yingnan and Tian, Jiarui and Sun, Han and Song, Fengling
Journal: Chembiochem : a European journal of chemical biology (2022): e202200421
Authors: Sun, Jinghan and Feng, Erting and Shao, Yutong and Lv, Fangyuan and Wu, Yingnan and Tian, Jiarui and Sun, Han and Song, Fengling
Journal: Chembiochem : a European journal of chemical biology (2022): e202200421
Eradication of solid tumors by chemodynamic theranostics with H2O2-catalyzed hydroxyl radical burst.
Authors: Wang, Nana and Zeng, Qin and Zhang, Ruijing and Xing, Da and Zhang, Tao
Journal: Theranostics (2021): 2334-2348
Authors: Wang, Nana and Zeng, Qin and Zhang, Ruijing and Xing, Da and Zhang, Tao
Journal: Theranostics (2021): 2334-2348
Targeted antimicrobial peptide delivery in vivo to tumor with near infrared photoactivated mesoporous silica nanoparticles.
Authors: Dong, Weibing and Wen, Jia and Li, Yue and Wang, Cui and Sun, Shiguo and Shang, Dejing
Journal: International journal of pharmaceutics (2020): 119767
Authors: Dong, Weibing and Wen, Jia and Li, Yue and Wang, Cui and Sun, Shiguo and Shang, Dejing
Journal: International journal of pharmaceutics (2020): 119767
Supramolecular Nanodiscs Self-Assembled from Non-Ionic Heptamethine Cyanine for Imaging-Guided Cancer Photothermal Therapy.
Authors: Mu, Xueluer and Lu, Yingxi and Wu, Fapu and Wei, Yuhan and Ma, Huihui and Zhao, Yingjie and Sun, Jing and Liu, Shaofeng and Zhou, Xianfeng and Li, Zhibo
Journal: Advanced materials (Deerfield Beach, Fla.) (2020): e1906711
Authors: Mu, Xueluer and Lu, Yingxi and Wu, Fapu and Wei, Yuhan and Ma, Huihui and Zhao, Yingjie and Sun, Jing and Liu, Shaofeng and Zhou, Xianfeng and Li, Zhibo
Journal: Advanced materials (Deerfield Beach, Fla.) (2020): e1906711
Evaluation of COC183B2 antibody targeting ovarian cancer by near-infrared fluorescence imaging.
Authors: Zhang, Chen and Ling, Xinyu and Guo, Yanxiu and Yuan, Cunzhong and Cheng, Hongyan and Ye, Xue and Ma, Ruiqiong and Zhang, Yinli and Li, Yi and Chang, Xiaohong and Kong, Beihua and Liu, Tao and Cui, Heng
Journal: Chinese journal of cancer research = Chung-kuo yen cheng yen chiu (2019): 673-685
Authors: Zhang, Chen and Ling, Xinyu and Guo, Yanxiu and Yuan, Cunzhong and Cheng, Hongyan and Ye, Xue and Ma, Ruiqiong and Zhang, Yinli and Li, Yi and Chang, Xiaohong and Kong, Beihua and Liu, Tao and Cui, Heng
Journal: Chinese journal of cancer research = Chung-kuo yen cheng yen chiu (2019): 673-685
PEGylated cyanine dye nanoparticles as photothermal agents for mosquito and cancer cell control.
Authors: Xu, Qi and Shen, Yujun and Zhang, Yongchao and Shao, Xusheng
Journal: Bioorganic & medicinal chemistry letters (2019): 2398-2404
Authors: Xu, Qi and Shen, Yujun and Zhang, Yongchao and Shao, Xusheng
Journal: Bioorganic & medicinal chemistry letters (2019): 2398-2404
Mesenchymal stromal cell-derived nanovesicles ameliorate bacterial outer membrane vesicle-induced sepsis via IL-10.
Authors: Park, Kyong-Su and Svennerholm, Kristina and Shelke, Ganesh V and Bandeira, Elga and Lässer, Cecilia and Jang, Su Chul and Chandode, Rakesh and Gribonika, Inta and Lötvall, Jan
Journal: Stem cell research & therapy (2019): 231
Authors: Park, Kyong-Su and Svennerholm, Kristina and Shelke, Ganesh V and Bandeira, Elga and Lässer, Cecilia and Jang, Su Chul and Chandode, Rakesh and Gribonika, Inta and Lötvall, Jan
Journal: Stem cell research & therapy (2019): 231
Oridonin-loaded and GPC1-targeted gold nanoparticles for multimodal imaging and therapy in pancreatic cancer.
Authors: Qiu, Wenli and Chen, Rong and Chen, Xiao and Zhang, Huifeng and Song, Lina and Cui, Wenjing and Zhang, Jingjing and Ye, Dandan and Zhang, Yifen and Wang, Zhongqiu
Journal: International journal of nanomedicine (2018): 6809-6827
Authors: Qiu, Wenli and Chen, Rong and Chen, Xiao and Zhang, Huifeng and Song, Lina and Cui, Wenjing and Zhang, Jingjing and Ye, Dandan and Zhang, Yifen and Wang, Zhongqiu
Journal: International journal of nanomedicine (2018): 6809-6827
A Fluorescent Cy7-Mercaptopyridine for the Selective Detection of Glutathione over Homocysteine and Cysteine.
Authors: Yoon, Shin A and Kim, Wantae and Sharma, Amit and Verwilst, Peter and Won, Miae and Lee, Min Hee
Journal: Sensors (Basel, Switzerland) (2018)
Authors: Yoon, Shin A and Kim, Wantae and Sharma, Amit and Verwilst, Peter and Won, Miae and Lee, Min Hee
Journal: Sensors (Basel, Switzerland) (2018)
Achieving effective terminal exciton delivery in quantum dot antenna-sensitized multistep DNA photonic wires.
Authors: Spillmann, Christopher M and Ancona, Mario G and Buckhout-White, Susan and Algar, W Russ and Stewart, Michael H and Susumu, Kimihiro and Huston, Alan L and Goldman, Ellen R and Medintz, Igor L
Journal: ACS nano (2013): 7101-18
Authors: Spillmann, Christopher M and Ancona, Mario G and Buckhout-White, Susan and Algar, W Russ and Stewart, Michael H and Susumu, Kimihiro and Huston, Alan L and Goldman, Ellen R and Medintz, Igor L
Journal: ACS nano (2013): 7101-18