TRITC–dextran conjugate (average MW = ~20K)

TRITC-labeled dextran is used in cardiovascular, microcirculation, perfusion, cell monolayer and cell membrane permeability research as fluorescent flux tracer compound that supports the measurement of processes such as blood flow, membrane damage, vascular drainage and renal elimination. It is also used in microcirculation and cell permeability research utilizing microfluorimetry, and possible in perfusion studies in animals. TRITC-dextran has also been used to study plant cell wall porosity and capillary permeability. Plasma proteins have been shown not to bind to TRITC-dextran. Small TRITC-dextrans are often used to measure processes such as endocytosis and cell junction permeability. Rhodamine-dextran, 20 kDa, may be used to study cell processes (such as endocytosis and osmoporation), endothelial or epithelial monolayer porosity, apical-basolateral movements within cell layers and cell junction permeability and drug release from structures such as hydrogens and collagen minirods.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
21706	25 mg	Price

Citations

View all 7 citations: Citation Explorer

SIRB, sans iron oxide rhodamine B, a novel cross-linked dextran nanoparticle, labels human neuroprogenitor and SH-SY5Y neuroblastoma cells and serves as a USPIO cell labeling control

Authors:

Shen, W. B., Vaccaro, D. E., Fishman, P. S., Groman, E. V., Yarowsky, P.

Journal:

Contrast Media Mol Imaging (2016): 222-8

In vivo retrograde labeling of neurons in the zebrafish embryo or larva with rhodamine dextran

Authors:

Volkmann, K., Koster, R. W.

Journal:

CSH Protoc (2007): pdb prot4832

Tracing of axonal connectivities in a combined slice preparation of rat brains--a study by rhodamine-dextran-amine-application in the lateral nucleus of the amygdala

Authors:

von Bohlen und Halbach, O., Albrecht, D.

Journal:

J Neurosci Methods (1998): 169-75

Multiple anterograde tracing, combining Phaseolus vulgaris leucoagglutinin with rhodamine- and biotin-conjugated dextran amine

Authors:

Dolleman-Van der Weel, M. J., Wouterlood, F. G., Witter, M. P.

Journal:

J Neurosci Methods (1994): 9-21

Tracing of axonal connections by rhodamine-dextran-amine in the rat hippocampal-entorhinal cortex slice preparation

Authors:

Boulton, C. L., von Haebler, D., Heinemann, U.

Journal:

Hippocampus (1992): 99-106

Physical properties

Molecular weight	~21000
Solvent	Water

Spectral properties

Correction factor (260 nm)	0.27
Correction factor (280 nm)	0.34
Extinction coefficient (cm ^-1 M ^-1)	100000
Excitation (nm)	544
Emission (nm)	570

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501

Documents

Protocol
Safety Data Sheet
Certificate of Analysis

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Page updated on October 28, 2025