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AAT Bioquest

WSP-1 *CAS 1352750-34-5*

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Physical properties
Molecular weight561.65
SolventDMSO
Storage, safety and handling
Certificate of OriginDownload PDF
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageFreeze (< -15 °C); Minimize light exposure
UNSPSC12352200

OverviewpdfSDSpdfProtocol


CAS
1352750-34-5
Molecular weight
561.65
Hydrogen sulfide (H2S) is an important gaseous mediator, like nitric oxide, that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. WSP-1 is a reactive disulfide-containing, fluorescent probe designed to detect H2S in biological samples and cells. Through a reaction-based fluorescent turn-on strategy, WSP-1 selectively and rapidly reacts with H2S to generate benzodithiolone and a fluorophore with excitation and emission maxima of 465 and 515 nm, respectively.

Calculators


Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of WSP-1 *CAS 1352750-34-5* to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

0.1 mg0.5 mg1 mg5 mg10 mg
1 mM178.047 µL890.234 µL1.78 mL8.902 mL17.805 mL
5 mM35.609 µL178.047 µL356.094 µL1.78 mL3.561 mL
10 mM17.805 µL89.023 µL178.047 µL890.234 µL1.78 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

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Citations


View all 1 citations: Citation Explorer
Biodegradable calcium sulfide-based nanomodulators for H2S-boosted Ca2+-involved synergistic cascade cancer therapy
Authors: Lin, Chuchu and Huang, Chenyi and Shi, Zhaoqing and Ou, Meitong and Sun, Shengjie and Yu, Mian and Chen, Ting and Yi, Yunfei and Ji, Xiaoyuan and Lv, Feng and others,
Journal: Acta Pharmaceutica Sinica B (2022)

References


View all 2 references: Citation Explorer
In site bioimaging of hydrogen sulfide uncovers its pivotal role in regulating nitric oxide-induced lateral root formation
Authors: Li YJ, Chen J, Xian M, Zhou LG, Han FX, Gan LJ, Shi ZQ.
Journal: PLoS One (2014): e90340
Selenium inhibits root elongation by repressing the generation of endogenous hydrogen sulfide in Brassica rapa
Authors: Chen Y, Mo HZ, Zheng MY, Xian M, Qi ZQ, Li YQ, Hu LB, Chen J, Yang LF.
Journal: PLoS One (2014): e110904