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AAT Bioquest

XFD660 Maleimide

XFD660, synthesized by AAT Bioquest, is chemically identical to Alexa Fluor® 660 (a ThermoFisher trademark). Designed for optimal excitation at 633 or 647 nm laser lines, XFD660 is well-suited for advanced imaging and flow cytometry applications, offering excellent fluorescence brightness and photostability. This dye is water-soluble and demonstrates pH stability within a range from 4 to 10. The maleimide derivative of XFD660 is commonly utilized for conjugation to thiol groups on proteins, oligonucleotide thiophosphates, or low molecular weight ligands, producing conjugates that exhibit significantly brighter fluorescence and enhanced photostability compared to those formed with other spectrally similar fluorophores.

Spectrum

References

View all 37 references: Citation Explorer
A decade of blood-brain barrier permeability assays: Revisiting old traumatic brain injury rat data for new insights and experimental design.
Authors: Bolden, Chris T and Olson, Scott D and Cox, Charles S
Journal: Microvascular research (2023): 104453
A novel anti-TNF-α drug ozoralizumab rapidly distributes to inflamed joint tissues in a mouse model of collagen induced arthritis.
Authors: Oyama, Shohei and Ebina, Kosuke and Etani, Yuki and Hirao, Makoto and Kyuuma, Masanao and Fujii, Yasuyuki and Iwata, Katsuya and Ogawa, Bunichiro and Hasegawa, Tomoya and Kawano, Sasagu and Nakanishi, Yutaka and Okada, Seiji and Nakata, Ken
Journal: Scientific reports (2022): 18102
CD38-specific nanobodies allow in vivo imaging of multiple myeloma under daratumumab therapy.
Authors: Pape, Luca Julius and Hambach, Julia and Gebhardt, Anna Josephine and Rissiek, Björn and Stähler, Tobias and Tode, Natalie and Khan, Cerusch and Weisel, Katja and Adam, Gerhard and Koch-Nolte, Friedrich and Bannas, Peter
Journal: Frontiers in immunology (2022): 1010270
A 15-min non-competitive homogeneous assay for microcystin and nodularin based on time-resolved Förster resonance energy transfer (TR-FRET).
Authors: Akter, Sultana and Lamminmäki, Urpo
Journal: Analytical and bioanalytical chemistry (2021): 6159-6170
Alpha-MSH Targeted Liposomal Nanoparticle for Imaging in Inflammatory Bowel Disease (IBD).
Authors: Peñate-Medina, Tuula and Damoah, Christabel and Benezra, Miriam and Will, Olga and Kairemo, Kalevi and Humbert, Jana and Sebens, Susanne and Peñate-Medina, Oula
Journal: Current pharmaceutical design (2020): 3840-3846
Page updated on September 15, 2024

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Catalog Number1892
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Physical properties

Molecular weight

1016.09

Solvent

DMSO

Spectral properties

Extinction coefficient (cm -1 M -1)

132000

Excitation (nm)

663

Emission (nm)

691

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Freeze (< -15 °C); Minimize light exposure
UNSPSC12171501