XFD750 amine is the same molecule to the Alexa Fluor® 750 amine (Alexa Fluor® is the trademark of ThermoFisher). It is a cyanine dye with bright NIR-fluorescence optimal for labeling antibodies. It has the identical spectra to Cy7 dye. XFD750 dye is water soluble and pH-insensitive from pH 4 to 10. The amine of XFD750 is a versatile carbonyl-reactive form for conjugating this fluorophore to peptides and other biological molecules.

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Catalog Number	1710
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Physical properties

Molecular weight	1155.17
Solvent	DMSO

Spectral properties

Correction Factor (280 nm)	0.04
Correction Factor (565 nm)	0.0277
Correction Factor (650 nm)	0.1505
Extinction coefficient (cm ^-1 M ^-1)	290000
Excitation (nm)	752
Emission (nm)	776
Quantum yield	0.12¹

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure

Spectrum

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Product family

Name	Excitation (nm)	Emission (nm)	Extinction coefficient (cm ^-1 M ^-1)	Quantum yield	Correction Factor (280 nm)
XFD488 amine Same Structure to Alexa Fluor™ 488 amine	499	520	71000	0.92¹	0.11
XFD594 amine Same Structure to Alexa Fluor™ 594 amine	590	618	90000	0.66¹	0.56
XFD532 amine	534	553	81000	0.61¹	0.09
XFD555 amine	553	568	155000	0.1¹	0.08
XFD568 amine	579	603	88000	0.69¹	0.46
XFD647 amine	650	671	270000	0.33¹	0.03
ICG amine	789	813	230000	-	0.076

References

View all 31 references: Citation Explorer

pH-responsive graphene oxide loaded with targeted peptide and anticancer drug for OSCC therapy.
Authors: Li, Ran and Gao, Ruifang and Zhao, Yingjiao and Zhang, Fang and Wang, Xiangyu and Li, Bing and Wang, Lu and Ma, Lixin and Du, Jie
Journal: Frontiers in oncology (2022): 930920

Near-Infrared Fluorescence Imaging of Carotid Plaques in an Atherosclerotic Murine Model.
Authors: Wu, Xiaotian and Daniel Ulumben, Amy and Long, Steven and Katagiri, Wataru and Wilks, Moses Q and Yuan, Hushan and Cortese, Brian and Yang, Chengeng and Kashiwagi, Satoshi and Choi, Hak Soo and Normandin, Marc D and El Fakhri, Georges and Zaman, Raiyan T
Journal: Biomolecules (2021)

Challenging a Preconception: Optoacoustic Spectrum Differs from the Optical Absorption Spectrum of Proteins and Dyes for Molecular Imaging.
Authors: Fuenzalida Werner, Juan Pablo and Huang, Yuanhui and Mishra, Kanuj and Janowski, Robert and Vetschera, Paul and Heichler, Christina and Chmyrov, Andriy and Neufert, Clemens and Niessing, Dierk and Ntziachristos, Vasilis and Stiel, Andre C
Journal: Analytical chemistry (2020)

CD24-targeted intraoperative fluorescence image-guided surgery leads to improved cytoreduction of ovarian cancer in a preclinical orthotopic surgical model.
Authors: Kleinmanns, Katrin and Fosse, Vibeke and Davidson, Ben and de Jalón, Elvira García and Tenstad, Olav and Bjørge, Line and McCormack, Emmet
Journal: EBioMedicine (2020): 102783

Mechanistic profiling of the release kinetics of siRNA from lipidoid-polymer hybrid nanoparticles in vitro and in vivo after pulmonary administration.
Authors: Thanki, Kaushik and van Eetvelde, Delphine and Geyer, Antonia and Fraire, Juan and Hendrix, Remi and Van Eygen, Hannelore and Putteman, Emma and Sami, Haider and de Souza Carvalho-Wodarz, Cristiane and Franzyk, Henrik and Nielsen, Hanne Mørck and Braeckmans, Kevin and Lehr, Claus-Michael and Ogris, Manfred and Foged, Camilla
Journal: Journal of controlled release : official journal of the Controlled Release Society (2019): 82-93

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