Xylazine NHS Ester

Xylazine NHS ester is an excellent amino-reactive building block for developing assays and tests for detecting Xylazine. Xylazine is a non-opioid sedative or tranquilizer. It is not approved for use in people. It is commonly used in veterinary medicine for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle, and other mammals. In veterinary anesthesia, it is often combined with ketamine. Veterinarians also use xylazine as an emetic, especially in cats.

Product family

Name	Excitation (nm)	Emission (nm)	Extinction coefficient (cm ^-1 M ^-1)	Quantum yield	Correction Factor (260 nm)	Correction Factor (280 nm)
Cy2DIGE NHS ester	492	508	150000	0.120	0.08	0.15
Cy3B NHS ester	560	571	120000¹	0.58¹	0.048	0.069
Cy3DIGE NHS ester	555	569	150000¹	0.15¹	0.07	0.073
Cy5DIGE NHS ester	651	670	250000¹	0.27¹, 0.4²	0.02	0.03
CypHer5E NHS Ester	643	660	-	-	-	-
CypHer7E NHS Ester	748	769	-	-	-	-
QXY21 NHS ester [equivalent to QSY-21 NHS ester]	-	-	89000¹	-	-	0.32
QXY7 NHS ester [equivalent to QSY-7 NHS ester]	-	-	90000¹	-	-	0.22
XFD350 NHS Ester	343	441	19000	-	0.25	0.19
XFD430 NHS ester	432	540	15,000	-	-	0.28
XFD488 NHS Ester	499	520	71000	0.92¹	0.30	0.11
XFD514 NHS Ester	518	543	80000	-	0.31	0.18
XFD532 NHS Ester	534	553	81000	0.61¹	0.24	0.09
XFD546 NHS Ester	561	572	112000	0.79¹	0.21	0.12
XFD555 NHS Ester	553	568	150000	0.1¹	0.08	0.08
XFD568 NHS Ester	579	603	91300	0.69¹	0.45	0.46
XFD594 NHS Ester	590	618	90000	0.66¹	0.43	0.56
XFD647 NHS Ester	650	671	239000	0.33¹	0.00	0.03
XFD660 NHS Ester	663	691	132000	-	0.00	0.10
XFD680 NHS Ester	681	704	184000	0.36¹	0.00	0.05
XFD700 NHS Ester	696	719	192000	0.25¹	0.00	0.07
XFD750 NHS Ester	752	776	240000	0.12¹	0.00	0.04
XFD790 NHS Ester	782	805	260,000	-	0.09	0.08
Show More (14)

References

View all 6 references: Citation Explorer

Understanding sensitivity and cross-reactivity of xylazine lateral flow immunoassay test strips for drug checking applications.
Authors: Sisco, Edward and Nestadt, Danielle F and Bloom, Madeline B and Schneider, Kristin E and Elkasabany, Rae A and Rouhani, Saba and Sherman, Susan G
Journal: Drug testing and analysis (2023)

Xylazine in the drug supply: Emerging threats and lessons learned in areas with high levels of adulteration.
Authors: Quijano, Thomas and Crowell, Jason and Eggert, Kathryn and Clark, Katie and Alexander, Marcus and Grau, Lauretta and Heimer, Robert
Journal: The International journal on drug policy (2023): 104154

A Confirmed Case of Xylazine-Induced Skin Ulcers in a Person Who Injects Drugs in Miami, Florida, USA.
Authors: Warp, Peyton V and Hauschild, Maia and Tookes, Hansel E and Ciraldo, Katrina and Serota, David P and Cruz, Irasema
Journal: Research square (2023)

Harm reduction and emergency medical services: Opportunities for evidence-based programming.
Authors: Friedman, Nicholas M G and Molina, Caitlin A and Glenn, Melody J
Journal: The American journal of emergency medicine (2023): 85-87

Perspectives of people in Philadelphia who use fentanyl/heroin adulterated with the animal tranquilizer xylazine; Making a case for xylazine test strips.
Authors: Reed, Megan K and Imperato, Nicholas S and Bowles, Jeanette M and Salcedo, Venise J and Guth, Amanda and Rising, Kristin L
Journal: Drug and alcohol dependence reports (2022): 100074

Page updated on August 15, 2025

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