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AAT Bioquest

What are the applications of the Ames test?

Posted March 24, 2021


Answer

The Ames test's main application is to determine whether or not a chemical substance is mutagenic and can cause DNA mutations. It is used regularly within the agricultural, pharmaceutical, and cosmetic industries to test the potential risk of a pesticide, drug, or cosmetic. A positive Ames test typically results in the pesticide, drug, or cosmetic product being withdrawn from medical or commercial use.

Additional resources

Development, qualification, validation and application of the Ames test using a VITROCELL® VC10® smoke exposure system

BrUTP [5-Bromouridine 5'-triphosphate] *10 mM in TE buffer* *CAS 161848-60-8*