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AAT Bioquest

What are the difference between an operator and a promoter?

Posted October 21, 2020


Answer

Operators and promoters are vital DNA sequences that are involved in the transcription process. These are the key differences between an operator and a promoter:

Basis for comparison

OperatorPromoter
DefinitionA specific section of DNA where transcription factors bind, inhibiting transcriptionA specific sequence of DNA where transcription begins
PresenceFound only in prokaryotesFound in prokaryotes and eukaryotes
FunctionRegulate gene expression by binding the repressor and inhibiting transcription of downstream genes Controls gene expression by signaling the RNA polymerase to begin transcription and in which direction the polymerase should transcribe the DNA 
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