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What is the difference between Myc and c-Myc tag proteins?
Posted April 24, 2020
Antibodies and Proteomics Enzyme-Linked Immunosorbent Assay (ELISA)Antibody and Protein LabelingImmunohistochemistry (IHC)ProteinWestern Blot
Answer
The Myc and c-Myc tag are two terms for the same tag, which is derived from the c-Myc protein and has a peptide sequence of EQKLISEEDL. The tag is used to label target proteins to enable easier identification or purification.
Additional resources
MYC AntibodyHilpert, K., Hansen, G., Wessner, H., Küttner, G., Welfle, K., Seifert, M., & Höhne, W. (2001). Anti-c-myc antibody 9E10: epitope key positions and variability characterized using peptide spot synthesis on cellulose. Protein Engineering, Design and Selection, 14(10), 803–806. doi:10.1093/protein/14.10.803