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AAT Bioquest

What is the molecular weight (mw) of Glyceraldehyde phosphate dehydrogenase (GADPH)?

Posted February 8, 2018


Answer

144 kDa

 

GADPH is a tetramer with a total molecular weight of 144,000 daltons.  All four subunits: O, Q, R, and P are independent of each other, however each subunit contains the coenzyme NAD+ (11).  Each subunit also contains 331 residues with molecular weights of 36,000 daltons.

Additional resources

Amino-acid Sequence of Glyceraldehyde 3-Phosphate Dehydrogenase from Lobster Muscle

Subunit structure of glyceraldehyde-3-phosphate dehydrogenase