How do polymer-based methods work? | AAT Bioquest

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How do polymer-based methods work?

Posted May 8, 2024

Antibodies and Proteomics Bioconjugation Chemical Reagents Antibody and Protein Labeling Immunohistochemistry (IHC)

Answer

Polymer-based methods utilize numerous peroxidase molecules and secondary antibodies, which are linked to a dextran polymer backbone. This configuration improves both sensitivity and specificity compared to streptavidin-biotin-based systems.

Additional resources

An Introduction to the Performance of Immunohistochemistry Immunohistochemistry (IHC) ReadiUse™ Stayright™ Purple *HRP Chromogen Premixed with Hydrogen Peroxide*

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