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What are the differences between bacteria and eukaryotes?
Posted February 9, 2023

Answer

Basis of differentiation

Bacteria 

Eukaryotes

Piody
Haploid
Diploid
Genetic reassortment
Infrequent short gene conversion and horizontal gene transfer events
Homologous recombination and chromosome segregation linked to reproduction
Origin
Bacteria were colonized and abundant for over a billion years before eukaryotes existed
Eukaryotes originated approximately 1-1.5 billion years after prokaryotes 
Size 
Most bacterial cells are extremely small (1 micrometer in diameter)
Eukaryotic cells range from 10-100 micrometers in size 
Ribosomes
Bacteria have 70 S ribosomes
Eukaryotes have 80 S ribosomes 
Modification of RNA
No mRNA modifications occur in bacteria
mRNA modifications occur after transcription  
Transcription and translation
Transcription and translated are coupled in bacteria 
Transcription and translation occur individually in eukaryotes
Introns and repetitive sequences
Introns and repetitive sequences are not present in bacteria 
Introns and repetitive sequences are present in bacteria
Initiation of protein synthesis 
Protein synthesis of bacteria is initiated by formyl-methionine
Protein synthesis is initiated by methionine
Internal compartments 
Bacteria do not contain any internal compartments or an internal membrane system
Eukaryotes contain internal compartments and an internal membrane system 
Reproduction
Bacteria produce asexually (binary fission)
Mitosis occurs in eukaryotes
Chromosomes
Single circular DNA is present in bacteria
Proteins and DNA are complexed to form multiple chromosomes 
Flagella
Some bacterial cells contain a simple flagella that are made out of a single fiber of flagellin protein
Some eukaryotes have a complex flagella and cilia with a structure of 9+2 arrangement of microtubules 
Unicellular or multicellular
All bacterial cells are unicellular
Eukaryotes can either be unicellular or multicellular