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What are the differences between bacteria and viruses?
Posted July 25, 2024

Answer
Basis of differentiation 
Bacteria 
Viruses 
Definition 
Are free-living cells that can live inside or outside a body
Are non-living collection of molecules that need a host to survive
Number of cells
One cell (unicellular)
No cells (acellular) 
Size 
Large, 900 - 1000 nm
Smaller 30-500 nm
Visibility 
Visible under Light Microscope
Visible only under Electron Microscope
Cell wall
Has a cell wall composed of Peptidoglycan or Lipopolysaccharide
Does not have a cell wall, instead the genetic material is enveloped by a protein coat known as a capsid
Cellular machinery 
Possesses a cellular machinery
Lack cellular machinery
Characteristics of DNA and RNA
DNA and RNA float freely in cytoplasm
DNA or RNA are enclosed inside a coat of protein known as capsid
Ribosomes 
Present 
Absent 
nucleus
no
no
Ability to reproduce 
Able to reproduce by itself
Need a living cell to reproduce
Mode of reproduction 
Asexually by binary fission, which is a form of asexual reproduction
Invade a cell host and insert their genome in the host genome, making multiple copies of the viral DNA/RNA, thus destroying the host cell and releasing new viruses
Mode & Type of infection
Opportunistic and localized infection – Bacteria typically infect the host when the opportunity arises and the infection is confined to one part of the body
Systemic infection – After infecting a host cell viruses multiply by the thousands, leaving the host cell and spreading the infection throughout the body 
Common diseases caused
Tetanus, food poisoning, gastritis and ulcers, meningitis, pneumonia, and tuberculosis
Influenza, AIDS, common cold, measles, chickenpox, polio and COVID-19
Duration of illness
Longer than 10 days
About 2 to 10 days
Treatment 
Antibiotics are an effective treatment
Do not respond to antibiotics. Antiviral drugs and vaccines prevent the spread of viruses and slow reproduction
Virulence
yes
yes
Fever 
Bacterial infection typically causes a fever
Viral infection may or may not cause a fever
Examples 
Staphylococcus aureus, Vibrio cholerae, 
HIV, Hepatitis A virus, RhinoVirus,