What are the differences between ion exchange chromatography and ion chromatography?

Question

Accepted Answer

Basis of differentiation

Ion exchange chromatography

Ion pair chromatography

Definition

Is a form of liquid chromatography to separate organic and inorganic molecules

Is a technique in which ions in a sample are paired and separated as ion pairs

Stationary Phase

Contains charged functional groups (anion or cation exchange resins)

Typically nonpolar reversed-phase columns

Reproducibility

Low

Very high

Separation time

High

Low

Separation mechanism

Ion exchange between sample ions and stationary phase

Formation of ion pairs between sample ions and ion pairing reagent

Basis of differentiation	Ion exchange chromatography	Ion pair chromatography
Definition	Is a form of liquid chromatography to separate organic and inorganic molecules	Is a technique in which ions in a sample are paired and separated as ion pairs
Stationary Phase	Contains charged functional groups (anion or cation exchange resins)	Typically nonpolar reversed-phase columns
Reproducibility	Low	Very high
Separation time	High	Low
Separation mechanism	Ion exchange between sample ions and stationary phase	Formation of ion pairs between sample ions and ion pairing reagent