What are the differences between lymphocytes and lymphoblasts?

Question

Accepted Answer

Basis of differentiation

Lymphoblast

Lymphocyte

Definition

Is an immature white blood cell that acts as a progenitor for lymphocyte

Is a mature white blood cell that is derived from lymphoblast

Location

Found mainly in the red bone marrow

Found in various parts of the body, mainly the thymus, blood, and spleen

Size

Around 10-18 µm

Around 17-20 µm

Number of nucleoli

Contains 1 – 2 nucleoli

Does not contain nucleoli

Cytoplasmic granules

Absent

Few azurophilic granules may be found

Nuclear-cytoplasmic ratio

4:1

2:1

Chromatin

May have fine nuclear chromatin or condensed chromatin

Chromatin is dense and clumped

Basis of differentiation	Lymphoblast	Lymphocyte
Definition	Is an immature white blood cell that acts as a progenitor for lymphocyte	Is a mature white blood cell that is derived from lymphoblast
Location	Found mainly in the red bone marrow	Found in various parts of the body, mainly the thymus, blood, and spleen
Size	Around 10-18 µm	Around 17-20 µm
Number of nucleoli	Contains 1 – 2 nucleoli	Does not contain nucleoli
Cytoplasmic granules	Absent	Few azurophilic granules may be found
Nuclear-cytoplasmic ratio	4:1	2:1
Chromatin	May have fine nuclear chromatin or condensed chromatin	Chromatin is dense and clumped