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What are the differences between proteinase K and protease?
Posted May 19, 2023
Answer
Proteinase K and protease are two types of protein-cleaving enzymes. While both are capable of cleaving peptide bonds in proteins, they differ considerably in the way they work and their uses.
Proteinase K
Proteinase K is a broad-spectrum serine protease enzyme that acts mainly on keratin protein. It plays a key role in digestion of proteins and eliminating contamination from nucleic acid preparations.
Protease
Protease is an enzyme catalyzing proteolysis. It acts mainly on the proteins in foods and plays a key role in multiple biological functions including cell signaling, digestion of ingested proteins, and protein catabolism.