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AAT Bioquest

What are the differences between serial dilution and serial logarithmic dilution?

Posted January 9, 2024


Answer

Basis of differentiation

Serial dilution

Serial logarithmic dilution

Definition

Serial dilution involves a step-by-step process of repeatedly diluting a concentrated solution to achieve a more manageable concentration 

Is a logarithmic reduction of concentration

Concentration reduction

Is gradually and steadily reduced

Is reduced faster in higher increments

Dilution factor

Constant dilution factor (e.g. 1:10)

Exponential dilution factor (e.g. 1:100)

   
Additional resources

Serial Dilutions and Plating: Microbial Enumeration

Serial Dilution Calculator and Planner