Basis of differentiation

Serial dilution

Simple dilution

Definition

Serial dilution involves a step-by-step process of repeatedly diluting a concentrated solution to achieve a more manageable concentration 

A simple dilution involves mixing a specific amount of a substance with an appropriate amount of a solvent to reach the desired concentration 

Method

Involves a series of dilutions

Involves a single dilution ratio 

Purpose

Used for accurate quantification of a sample

Is typically used for easier preparation of solutions

Concentration change

Gradual decrease/increase in concentration

Immediate change in concentration 

Process

Each step uses a portion of the previous dilution

Is a single step using one dilution factor