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AAT Bioquest

What are the functions of ATP synthase?

Posted January 4, 2024


Answer

The primary functions of ATP synthase is to regulate ATP synthesis and transmembrane potential. ATP synthase is crucial since it is responsible for generating the highest number of ATP molecules in the body. ATP is converted from ADP by harnessing the energy created by the proton electrochemical gradient. About 32 molecules of ATP are generated from the oxidation of one glucose molecule. The ATP synthase involves the use of transmembrane potential, which is the difference in electric potential between the interior and exterior of the membrane. The potential difference is created by the movement of protons across the membrane. This mechanism converts electrochemical energy to mechanical energy and then back to ATP. 

Additional resources

The Role of the βDELSEED-loop of ATP Synthase

ATP & ADP

PhosphoWorks™ Fluorimetric ATP Assay Kit