AAT Bioquest

What is the magnitude of RMP in a typical skeletal muscle cell?

Posted October 16, 2023


The resting membrane potential in skeletal muscle cells is mostly due to the K+ concentration ratio across the sarcolemma membrane. This is because there is a larger number of K+ channels as compared to Na+ channels, and all cell membranes are more permeable to K+ than to Na+. 

The RMP in a typical skeletal muscle cell is -90 mV.

Additional resources

Signaling in Muscle Contraction

Screen Quest™ Membrane Potential Assay Kit *Red Fluorescence*