Caffeine Toxicity (LD50)

The median lethal dose (LD50) for Caffeine is

192 mg

per

*Value is measured via oral route in rat

Compound Information

Caffeine (Also known as: 1,3,7-Trimethylxanthine, Thein) appears as odorless white powder or white glistening needles, usually melted together. It is odorless and has a bitter taste. Caffeine is the most widely consumed psychostimulant drug in the world and is mostly consumed in the form of coffee. Solutions in water are neutral to litmus. The substance can be absorbed into the body by inhalation and by ingestion.

Molecular weight: 194.19Chemical formula: C₈H₁₀N₄O₂

Information presented on this page is purely for research purposes only. It is NOT intended for clinical or diagnostic applications. To request additional information and datasets for Caffeine, please contact info@aatbio.com.

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References

This online resource may be cited as follows

MLA	"Quest Database™ Caffeine Toxicity (LD50)." AAT Bioquest, Inc., 23 Oct. 2025, https://www.aatbio.com/resources/toxicity-lethality-median-dose-td50-ld50/caffeine.
APA	AAT Bioquest, Inc. (2025, October 23). Quest Database™ Caffeine Toxicity (LD50). AAT Bioquest. https://www.aatbio.com/resources/toxicity-lethality-median-dose-td50-ld50/caffeine.
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