Cannabidiol Toxicity (LD50)

The median lethal dose (LD50) for Cannabidiol is

980 mg

per

*Value is measured via oral route in rat

Compound Information

Cannabidiol (Also known as: (-)-Cannabidiol, CBD) is an orally available cannabinoid that is used to treat patients with refractory epilepsy due to Lennox-Gastaut or Dravet syndrome. Cannabidiol is associated with frequent serum enzyme elevations during therapy particularly with higher doses but has not been linked to cases of clinically apparent liver injury with jaundice. Chemically, cannabidiol is a cyclohexene which is substituted by a methyl group at position 1, a 2,6-dihydroxy-4-pentylphenyl group at position 3, and a prop-1-en-2-yl group at position 4.

Molecular weight: 314.5Chemical formula: C₂₁H₃₀O₂

Information presented on this page is purely for research purposes only. It is NOT intended for clinical or diagnostic applications. To request additional information and datasets for Cannabidiol, please contact info@aatbio.com.

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References

This online resource may be cited as follows

MLA	"Quest Database™ Cannabidiol Toxicity (LD50)." AAT Bioquest, Inc., 12 Feb. 2026, https://www.aatbio.com/resources/toxicity-lethality-median-dose-td50-ld50/cannabidiol.
APA	AAT Bioquest, Inc. (2026, February 12). Quest Database™ Cannabidiol Toxicity (LD50). AAT Bioquest. https://www.aatbio.com/resources/toxicity-lethality-median-dose-td50-ld50/cannabidiol.
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