Capsaicin Toxicity (LD50)

The median lethal dose (LD50) for Capsaicin is

47.2 mg

per

*Value is measured via oral route in mouse

Compound Information

Capsaicin (Also known as: Zostrix, Qutenza) is a capsaicinoid, often appearing as a pure dark red solid. It has a role as a non-narcotic analgesic, a voltage-gated sodium channel blocker and a TRPV1 agonist. It is a powerful irritant-initial administration causes burning pain in mucus membranes and to lesser extent on skin. Capsaicin is identified as the primary pungent principle in Capsicum fruits. Hot chili peppers that belong to the plant genus Capsicum (family Solanaceae) are among the most heavily consumed spices throughout the world.

Molecular weight: 305.4Chemical formula: C₁₈H₂₇NO₃

Information presented on this page is purely for research purposes only. It is NOT intended for clinical or diagnostic applications. To request additional information and datasets for Capsaicin, please contact info@aatbio.com.

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References

This online resource may be cited as follows

MLA	"Quest Database™ Capsaicin Toxicity (LD50)." AAT Bioquest, Inc., 16 Nov. 2025, https://www.aatbio.com/resources/toxicity-lethality-median-dose-td50-ld50/capsaicin.
APA	AAT Bioquest, Inc. (2025, November 16). Quest Database™ Capsaicin Toxicity (LD50). AAT Bioquest. https://www.aatbio.com/resources/toxicity-lethality-median-dose-td50-ld50/capsaicin.
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