Ribosomes and lysosomes are both found within cells where they perform vital cellular functions. That’s basically where the similarities end. Here’s how these two structures are different from each other.
| Ribosomes | Lysosomes |
| Macromolecules, not enclosed by a membrane | Membrane-enclosed organelle |
| Consists of two subunits of different sizes | Consists of one unit |
| Size range: 20 nanometer to 30 nanometer | Size range: 0.1 micrometer to 1.2 micrometer |
| Found in eukaryotic and prokaryotic cells | Found only in eukaryotic cells |
| May be scattered unevenly in the cytoplasm or attached to the rough endoplasmic reticulum within the cytoplasm | Distributed evenly in the cytoplasm |
| Composed of rRNA and ribosomal proteins | Composed of membrane proteins and digestive enzymes |
| Plays a key role in synthesis of proteins and translation of mRNAs | Plays a key role in intracellular digestion and destruction of dead cells |