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5-FAM-YVAD-FMK
FAM-YVAD-FMK, i.e., 5-carboxyfluorescein-Tyr-Val-Ala-Asp-fluoromethylketone, binds irreversibly to active caspase 1 in stimulated cells. The fluorescent intensity of the FAM-YVAD-FMK signal is proportional to the amount of active caspase 1 and can be easily detected at by fluorescence microscopy, flow cytometer, or fluorescent microplate reader.
Chemical structure for 5-FAM-YVAD-FMK.
Chemical structure for 5-FAM-YVAD-FMK.
CatalogSize
Price
Quantity
1347325 Tests
Price
13483100 Tests
Price
 
Physical properties

Molecular weight854.84
SolventDMSO
Spectral properties

Correction factor (260 nm)0.32
Correction factor (280 nm)0.178
Extinction coefficient (cm -1 M -1)
83000
Excitation (nm)493
Emission (nm)517
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageFreeze (< -15 °C); Minimize light exposure
UNSPSC12352200
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Page updated on October 8, 2025