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APC Anti-human CD11c Antibody
3.9
3.9 is an anti-human monoclonal antibody that forms an immune complex with the CD11c antigen. CD11c (sometimes called CR4 or ITGAX) is a 145 - 150 kD single-pass type I membrane protein that is expressed on the surface of cells such as macrophages, B cells and dendritic cells. In some organisms, CD11c promotes angiogenesis, positively regulates myelination and is a promoter of endothelial tube morphogenesis. Moreover, it is a component of essential cellular pathways, in particular, the cytokine-mediated signaling pathway and integrin-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands like ICAM-1 and 4 and fibrinogen. CD11c is a very popular antibody target, with over 26000 publications in the last decade. CD11c has been widely used in costimulatory molecules research, commonly serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to APC (ex/em = 651/660 nm). It is compatible with the 642 nm laser and 664/20 nm bandpass filter (for example, as in the Luminex Guava easyCyte).
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Price
Quantity
101131C025 tests
Price
101131C1100 tests
Price
101131C2500 tests
Price
 
Antibody properties

Other namesIntegrin alpha-X, CR4, p150, ITGAX
Clone3.9
HostMouse
IsotypeIgG1, kappa
ReactivityHuman
Spectral properties

Correction factor (280 nm)0.195
Extinction coefficient (cm -1 M -1)
730000
Excitation (nm)651
Emission (nm)660
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
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Page updated on April 1, 2026