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Concanavalin A, XFD594 Labeled *XFD594 Same Structure to Alexa Fluor™ 594*
XFD594 is manufactured by AAT Bioquest, and it has the same chemical structure of Alexa Fluor® 594 (Alexa Fluor® is the trademark of ThermoFisher). Concanavalin A (ConA) is a lectin that binds specifically to certain structures found in various sugars, glycoproteins and glycolipids. ConA is widely used in biology and biochemistry to characterize glycoproteins and other sugar-containing entities on the surface of various cells. It is also used to purify glycosylated macromolecules in lectin affinity chromatography, as well as to study immune regulation by various immune cells. ConA binds specifically α-D-mannosyl and α-D-glucosyl residues (two hexoses differing only in the alcohol on carbon 2) in terminal position of ramified structures from B-Glycans. Concanavalin A (Con A) is one of the most widely used lectins in cell biology. XFD594-labeled Concanavalin A (equivalent to Alexa Fluor® 594 conjugate of Con A, Alexa Fluor® is the trademark of ThermoFisher) exhibits the bright, red fluorescence. XFD594 Con A selectively binds to a-mannopyranosyl and a-glucopyranosyl residues.
Spectrum
Product family
| Name | Excitation (nm) | Emission (nm) | Extinction coefficient (cm -1 M -1) | Quantum yield | Correction Factor (260 nm) | Correction Factor (280 nm) |
| Concanavalin A, XFD488 Labeled *XFD488 Same Structure to Alexa Fluor™ 488* | 499 | 520 | 73000 | 0.921 | 0.3 | 0.11 |
Citations
View all 1 citations: Citation Explorer
Alleviation of RO Membrane Fouling in Wastewater Reclamation Plants Using an Enhanced Acid-Base Chemical Cleaning Method
Authors: Li, Zihao and Wang, Jinlong and Cheng, Lihua and Yang, Qiang and Li, Peizhuo and Dong, Xiaowan and Xu, Boyan and Zhi, Mei and Hao, Anni and yong Ng, How and others,
Journal: Water Research (2024): 122039
Authors: Li, Zihao and Wang, Jinlong and Cheng, Lihua and Yang, Qiang and Li, Peizhuo and Dong, Xiaowan and Xu, Boyan and Zhi, Mei and Hao, Anni and yong Ng, How and others,
Journal: Water Research (2024): 122039
References
View all 50 references: Citation Explorer
ISFET and Dex-AgNPs based portable sensor for reusable and real-time determinations of concanavalin A and glucose on smartphone.
Authors: Zhao, Shuang and Shi, Cong and Hu, Hongyang and Li, Zhengping and Xiao, Gang and Yang, Qiaochun and Sun, Peng and Cheng, Linyang and Niu, Wencheng and Bi, Jinshun and Yue, Zhao
Journal: Biosensors & bioelectronics (2020): 111962
Authors: Zhao, Shuang and Shi, Cong and Hu, Hongyang and Li, Zhengping and Xiao, Gang and Yang, Qiaochun and Sun, Peng and Cheng, Linyang and Niu, Wencheng and Bi, Jinshun and Yue, Zhao
Journal: Biosensors & bioelectronics (2020): 111962
Montelukast ameliorates Concanavalin A-induced autoimmune hepatitis in mice via inhibiting TNF-α/JNK signaling pathway.
Authors: El-Kashef, Dalia H and Abdelrahman, Rehab S
Journal: Toxicology and applied pharmacology (2020): 114931
Authors: El-Kashef, Dalia H and Abdelrahman, Rehab S
Journal: Toxicology and applied pharmacology (2020): 114931
Acupuncture stimulation attenuates TNF-α production via vagal modulation in the concanavalin A model of hepatitis.
Authors: Lim, Hee-Don and Kim, Ki-Joong and Jo, Byung Gon and Park, Ji-Yeun and Namgung, Uk
Journal: Acupuncture in medicine : journal of the British Medical Acupuncture Society (2020): 964528420907338
Authors: Lim, Hee-Don and Kim, Ki-Joong and Jo, Byung Gon and Park, Ji-Yeun and Namgung, Uk
Journal: Acupuncture in medicine : journal of the British Medical Acupuncture Society (2020): 964528420907338
Deficiency of O-linked-glycosylation regulates activation of T cells and aggravates Concanavalin A-induced liver injury.
Authors: Hao, Xiaohua and Gao, Meixin and He, Lingling and Ye, Xiaohui and Yang, Junru and Zhang, Fuyang and Liu, Ran and Wei, Hongshan
Journal: Toxicology (2020): 152411
Authors: Hao, Xiaohua and Gao, Meixin and He, Lingling and Ye, Xiaohui and Yang, Junru and Zhang, Fuyang and Liu, Ran and Wei, Hongshan
Journal: Toxicology (2020): 152411
Nicotine attenuates concanavalin A-induced liver injury in mice by regulating the α7-nicotinic acetylcholine receptor in Kupffer cells.
Authors: Zhao, Jing and Park, Surim and Kim, Jong-Won and Qi, Jing and Zhou, Zixiong and Lim, Chae Woong and Kim, Bumseok
Journal: International immunopharmacology (2020): 106071
Authors: Zhao, Jing and Park, Surim and Kim, Jong-Won and Qi, Jing and Zhou, Zixiong and Lim, Chae Woong and Kim, Bumseok
Journal: International immunopharmacology (2020): 106071
Page updated on May 13, 2025
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