Concanavalin A, XFD594 Labeled *XFD594 Same Structure to Alexa Fluor™ 594*
Ordering information
| Price | |
| Catalog Number | |
| Unit Size | |
| Quantity |
Additional ordering information
| Telephone | 1-800-990-8053 |
| Fax | 1-800-609-2943 |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Shipping | Standard overnight for United States, inquire for international |
Physical properties
| Molecular weight | N/A |
| Solvent | Water |
Spectral properties
| Absorbance (nm) | 592 |
| Correction Factor (260 nm) | 0.43 |
| Correction Factor (280 nm) | 0.56 |
| Extinction coefficient (cm -1 M -1) | 92000 |
| Excitation (nm) | 590 |
| Emission (nm) | 618 |
| Quantum yield | 0.661 |
Storage, safety and handling
| H-phrase | H303, H313, H333 |
| Hazard symbol | XN |
| Intended use | Research Use Only (RUO) |
| R-phrase | R20, R21, R22 |
| Storage | Freeze (< -15 °C); Minimize light exposure |
| UNSPSC | 12171501 |
| Overview |  SDSProtocol |
See also: Antibody and Protein Labeling
Molecular weight N/A | Absorbance (nm) 592 | Correction Factor (260 nm) 0.43 | Correction Factor (280 nm) 0.56 | Extinction coefficient (cm -1 M -1) 92000 | Excitation (nm) 590 | Emission (nm) 618 | Quantum yield 0.661 |
XFD594 is manufactured by AAT Bioquest, and it has the same chemical structure of Alexa Fluor® 594 (Alexa Fluor® is the trademark of ThermoFisher). Concanavalin A (ConA) is a lectin that binds specifically to certain structures found in various sugars, glycoproteins and glycolipids. ConA is widely used in biology and biochemistry to characterize glycoproteins and other sugar-containing entities on the surface of various cells. It is also used to purify glycosylated macromolecules in lectin affinity chromatography, as well as to study immune regulation by various immune cells. ConA binds specifically α-D-mannosyl and α-D-glucosyl residues (two hexoses differing only in the alcohol on carbon 2) in terminal position of ramified structures from B-Glycans. Concanavalin A (Con A) is one of the most widely used lectins in cell biology. XFD594-labeled Concanavalin A (equivalent to Alexa Fluor® 594 conjugate of Con A, Alexa Fluor® is the trademark of ThermoFisher) exhibits the bright, red fluorescence. XFD594 Con A selectively binds to a-mannopyranosyl and a-glucopyranosyl residues.
Platform
Fluorescence microscope
| Excitation | Cy3/TRITC filter set |
| Emission | Cy3/TRITC filter set |
| Recommended plate | Black wall/clear bottom |
Spectrum
Open in Advanced Spectrum Viewer
Spectral properties
| Absorbance (nm) | 592 |
| Correction Factor (260 nm) | 0.43 |
| Correction Factor (280 nm) | 0.56 |
| Extinction coefficient (cm -1 M -1) | 92000 |
| Excitation (nm) | 590 |
| Emission (nm) | 618 |
| Quantum yield | 0.661 |
Product Family
| Name | Excitation (nm) | Emission (nm) | Extinction coefficient (cm -1 M -1) | Quantum yield | Correction Factor (260 nm) | Correction Factor (280 nm) |
| Concanavalin A, XFD488 Labeled *XFD488 Same Structure to Alexa Fluor™ 488* | 499 | 520 | 73000 | 0.921 | 0.3 | 0.11 |
References
View all 50 references: Citation Explorer
Short-term high-fat diet intake leads to exacerbation of concanavalin A-induced liver injury through the induction of procoagulation state.
Authors: Nanizawa, Eri and Tamaki, Yuki and Sono, Reika and Miyashita, Rintaro and Hayashi, Yumi and Kanbe, Ayumu and Ito, Hiroyasu and Ishikawa, Tetsuya
Journal: Biochemistry and biophysics reports (2020): 100736
Authors: Nanizawa, Eri and Tamaki, Yuki and Sono, Reika and Miyashita, Rintaro and Hayashi, Yumi and Kanbe, Ayumu and Ito, Hiroyasu and Ishikawa, Tetsuya
Journal: Biochemistry and biophysics reports (2020): 100736
Maresin 1 mitigates concanavalin A-induced acute liver injury in mice by inhibiting ROS-mediated activation of NF-κB signaling.
Authors: Zhang, Peng and Yin, Yuping and Wang, Tao and Li, Wei and Li, Chengguo and Zeng, Xiangyu and Yang, Wenchang and Zhang, Ruizhi and Tang, Yu and Shi, Liang and Li, Ruidong and Tao, Kaixiong
Journal: Free radical biology & medicine (2020): 23-36
Authors: Zhang, Peng and Yin, Yuping and Wang, Tao and Li, Wei and Li, Chengguo and Zeng, Xiangyu and Yang, Wenchang and Zhang, Ruizhi and Tang, Yu and Shi, Liang and Li, Ruidong and Tao, Kaixiong
Journal: Free radical biology & medicine (2020): 23-36
Membrane-associated gamma-glutamyl transferase and alkaline phosphatase in the context of concanavalin A- and wheat germ agglutinin-reactive glycans mark seminal prostasome populations from normozoospermic and oligozoospermic men.
Authors: Janković, Tamara and Goč, Sanja and Mitić, Ninoslav and Danilović Luković, Jelena and Janković, Miroslava
Journal: Upsala journal of medical sciences (2020): 10-18
Authors: Janković, Tamara and Goč, Sanja and Mitić, Ninoslav and Danilović Luković, Jelena and Janković, Miroslava
Journal: Upsala journal of medical sciences (2020): 10-18
Antioxidant Capacity and Hepatoprotective Role of Chitosan-Stabilized Selenium Nanoparticles in Concanavalin A-Induced Liver Injury in Mice.
Authors: Bai, Kaikai and Hong, Bihong and He, Jianlin and Huang, Wenwen
Journal: Nutrients (2020)
Authors: Bai, Kaikai and Hong, Bihong and He, Jianlin and Huang, Wenwen
Journal: Nutrients (2020)
The farnesyltransferase inhibitor tipifarnib protects against autoimmune hepatitis induced by Concanavalin A.
Authors: Guo, Jie and Shirozu, Kazuhiro and Akahoshi, Tomohiko and Mizuta, Yukie and Murata, Masaharu and Yamaura, Ken
Journal: International immunopharmacology (2020): 106462
Authors: Guo, Jie and Shirozu, Kazuhiro and Akahoshi, Tomohiko and Mizuta, Yukie and Murata, Masaharu and Yamaura, Ken
Journal: International immunopharmacology (2020): 106462
Concanavalin A-Rose Bengal bioconjugate for targeted Gram-negative antimicrobial photodynamic therapy.
Authors: Cantelli, Andrea and Piro, Francesca and Pecchini, Pietro and Di Giosia, Matteo and Danielli, Alberto and Calvaresi, Matteo
Journal: Journal of photochemistry and photobiology. B, Biology (2020): 111852
Authors: Cantelli, Andrea and Piro, Francesca and Pecchini, Pietro and Di Giosia, Matteo and Danielli, Alberto and Calvaresi, Matteo
Journal: Journal of photochemistry and photobiology. B, Biology (2020): 111852
Developmental exposure to low doses of dichlorodiphenyltrichloroethane impairs proliferative response of thymic lymphocytes to Concanavalin A in rats.
Authors: Yaglova, Nataliya V and Tsomartova, Elina S and Obernikhin, Sergey S and Ivanova, Marina Y and Chereshneva, Elizaveta V and Muhamedova, Svetlana G and Lomanovskaya, Tatiana A and Yaglov, Valentin V
Journal: Heliyon (2020): e03608
Authors: Yaglova, Nataliya V and Tsomartova, Elina S and Obernikhin, Sergey S and Ivanova, Marina Y and Chereshneva, Elizaveta V and Muhamedova, Svetlana G and Lomanovskaya, Tatiana A and Yaglov, Valentin V
Journal: Heliyon (2020): e03608
Concanavalin A Toxicity Towards Potato Psyllid and Apoptosis Induction in Midgut Cells.
Authors: Tang, Xiao-Tian and Ibanez, Freddy and Tamborindeguy, Cecilia
Journal: Insects (2020)
Authors: Tang, Xiao-Tian and Ibanez, Freddy and Tamborindeguy, Cecilia
Journal: Insects (2020)
Concanavalin A Enhanced Proliferation and Osteogenic Differentiation of Dental Pulp Stem Cells.
Authors: Suardita, Ketut and Arundina, Ira and Tedjosasongko, Udijanto and Yuliati, Anita and Peeters, Harry Huiz and Wijaksana, I Komang Evan and Surboyo, Meircurius Dwi Condro
Journal: European journal of dentistry (2020): 123-127
Authors: Suardita, Ketut and Arundina, Ira and Tedjosasongko, Udijanto and Yuliati, Anita and Peeters, Harry Huiz and Wijaksana, I Komang Evan and Surboyo, Meircurius Dwi Condro
Journal: European journal of dentistry (2020): 123-127
Mycophenolate mofetil attenuates concanavalin A-induced acute liver injury through modulation of TLR4/NF-κB and Nrf2/HO-1 pathways.
Authors: Serrya, Marwa S and Zaghloul, Marwa S
Journal: Pharmacological reports : PR (2020)
Authors: Serrya, Marwa S and Zaghloul, Marwa S
Journal: Pharmacological reports : PR (2020)