Estradiol-BSA conjugate

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Physical properties

Molecular weight	N/A
Solvent	Water

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501

Overview SDS Protocol

Molecular weight

N/A

Estradiol is an estrogen steroid hormone and the major female sex hormone. It is also called 17 beta-estradiol. Estradiol is involved in the regulation of the estrous and menstrual female reproductive cycles. It is responsible for the development of female secondary sexual characteristics and important in the development and maintenance of female reproductive tissues and pregnancy. It also has important effects in many other tissues including bone, fat, skin, liver, and the brain. Though estradiol levels in males are much lower compared to those in females, estradiol has important roles in males as well. An estradiol test measures the amount of the hormone estradiol in your blood. It is also called an E2 test. An estradiol test has a number of clinically important applications. Estradiol-BSA conjugate is a convenient building block for developing estradiol antibodies and assays.

Images

Figure 1. Chemical structure for Estradiol-BSA conjugate.

References

View all 43 references: Citation Explorer

Estrogen receptor-alpha isoforms are the main estrogen receptors expressed in non-small cell lung carcinoma.
Authors: Pelekanou, Vasiliki and Anastasiou, Eleftheria and Bakogeorgou, Efstathia and Notas, George and Kampa, Marilena and Garcia-Milian, Rolando and Lavredaki, Katerina and Moustou, Eleni and Chinari, Georgia and Arapantoni, Petroula and O'Grady, Anthony and Georgoulias, Vassilios and Tsapis, Andreas and Stathopoulos, Efstathios N and Castanas, Elias
Journal: Steroids (2019): 65-76

Surface plasmon resonance based indirect immunoassay for detection of 17β-estradiol.
Authors: Kumbhat, Sunita and Gehlot, Rakhee and Sharma, Kavita and Singh, Urvasini and Joshi, Vinod
Journal: Journal of pharmaceutical and biomedical analysis (2019): 211-216

Activation of G protein-coupled estrogen receptor 1 mimics, but does not mediate, the anti-proliferative action of estradiol on pituitary lactotrophs in primary culture.
Authors: Mitsui, Tetsuo and Ishida, Maho and Izawa, Michi and Arita, Jun
Journal: Endocrine journal (2017): 103-115

Estradiol induces osteoprotegerin expression by human dental pulp cells.
Authors: Manokawinchoke, Jeeranan and Ritprajak, Patcharee and Osathanon, Thanaphum and Pavasant, Prasit
Journal: Odontology (2016): 10-8

[Estradiol regulates the expression of small conductance Ca(2)+ activated K(+) channel 3 in rat colonic smooth muscle cells in an estrogen receptor α-dependent manner].
Authors: Yang, Wei-wei and Tang, Yu-rong and Wang, Yun and Li, Ping and Wang, Qing-e and Lin, Lin
Journal: Zhonghua yi xue za zhi (2013): 2367-71

Detection of estradiol at an electrochemical immunosensor with a Cu UPD|DTBP-Protein G scaffold.
Authors: Liu, Xiaoqiang and Wang, Xinhai and Zhang, Jiamei and Feng, Heqing and Liu, Xiuhua and Wong, Danny K Y
Journal: Biosensors & bioelectronics (2012): 56-62

Puerarin suppresses proliferation of endometriotic stromal cells partly via the MAPK signaling pathway induced by 17ß-estradiol-BSA.
Authors: Cheng, Wen and Chen, Lizao and Yang, Shengsheng and Han, Jie and Zhai, Dongxia and Ni, Jian and Yu, Chaoqin and Cai, Zailong
Journal: PloS one (2012): e45529

Estradiol pretreatment attenuated nicotine-induced endothelial cell apoptosis via estradiol functional membrane receptor.
Authors: Wang, Li-li and Zhao, Jian-li and Lau, Wayne-Bond and Zhang, Yan-qing and Qiao, Zhong-dong and Wang, Ya-jing
Journal: International immunopharmacology (2011): 675-82

17Beta-estradiol elevates cGMP and, via plasma membrane recruitment of protein kinase GIalpha, stimulates Ca2+ efflux from rat hepatocytes.
Authors: Stratton, Rebecca C and Squires, Paul E and Green, Anne K
Journal: The Journal of biological chemistry (2010): 27201-12

Estrogen and glucocorticoid regulate osteoblast differentiation through the interaction of bone morphogenetic protein-2 and tumor necrosis factor-alpha in C2C12 cells.
Authors: Matsumoto, Yoshinori and Otsuka, Fumio and Takano, Mariko and Mukai, Tomoyuki and Yamanaka, Ryutaro and Takeda, Masaya and Miyoshi, Tomoko and Inagaki, Kenichi and Sada, Ken-ei and Makino, Hirofumi
Journal: Molecular and cellular endocrinology (2010): 118-27