Fentanyl-KLH conjugate

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Additional ordering information

Telephone	1-800-990-8053
Fax	1-800-609-2943
Email	sales@aatbio.com
International	See distributors
Bulk request	Inquire
Custom size	Inquire
Shipping	Standard overnight for United States, inquire for international

Physical properties

Molecular weight	N/A
Solvent	Water

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501

Overview SDS Protocol

Molecular weight

N/A

Small compounds (drugs or peptides) are not sufficiently complex by themselves to induce an immune response or be processed in a manner that elicits production of specific antibodies. For antibody production to be successful with small antigens, they must be chemically conjugated with immunogenic carrier proteins such as keyhole limpet hemocyanin (KLH). Adjuvants can be mixed and injected with an immunogen to increase the intensity of the immune response. Fentanyl-KLH conjugate is widely used for developing fentanyl antibodies, assays and tests. Our Fentanyl-KLH conjugate is highly purified to maximize its immunization responses.

Images

Figure 1. Chemical structure for Fentanyl-KLH conjugate.

References

View all 46 references: Citation Explorer

A fentanyl vaccine constructed upon opsonizing antibodies specific for the Galα1-3Gal epitope.
Authors: Wang, Jiaxing and Ellis, Beverly and Zhou, Bin and Eubanks, Lisa M and Blake, Steven and Janda, Kim D
Journal: Chemical communications (Cambridge, England) (2020): 6551-6554

High Prevalence of Hepatitis C Infection Among Adult Patients at Four Urban Emergency Departments - Birmingham, Oakland, Baltimore, and Boston, 2015-2017.
Authors: Galbraith, James W and Anderson, Erik S and Hsieh, Yu-Hsiang and Franco, Ricardo A and Donnelly, John P and Rodgers, Joel B and Schechter-Perkins, Elissa M and Thompson, William W and Nelson, Noele P and Rothman, Richard E and White, Douglas A E
Journal: MMWR. Morbidity and mortality weekly report (2020): 569-574

Vaccine blunts fentanyl potency in male rhesus monkeys.
Authors: Tenney, Rebekah D and Blake, Steven and Bremer, Paul T and Zhou, Bin and Hwang, Candy S and Poklis, Justin L and Janda, Kim D and Banks, Matthew L
Journal: Neuropharmacology (2019): 107730

Monoclonal Antibodies for Combating Synthetic Opioid Intoxication.
Authors: Smith, Lauren C and Bremer, Paul T and Hwang, Candy S and Zhou, Bin and Ellis, Beverly and Hixon, Mark S and Janda, Kim D
Journal: Journal of the American Chemical Society (2019): 10489-10503

Psychopharmacology: neuroimmune signaling in psychiatric disease-developing vaccines against abused drugs using toll-like receptor agonists.
Authors: Yang, Fang and Kosten, Thomas R
Journal: Psychopharmacology (2019): 2899-2907

Rapid lateral flow assays based on the quantification of magnetic nanoparticle labels for multiplexed immunodetection of small molecules: application to the determination of drugs of abuse.
Authors: Guteneva, Natalia V and Znoyko, Sergey L and Orlov, Alexey V and Nikitin, Maxim P and Nikitin, Petr I
Journal: Mikrochimica acta (2019): 621

Development of vaccines to treat opioid use disorders and reduce incidence of overdose.
Authors: Pravetoni, Marco and Comer, Sandra D
Journal: Neuropharmacology (2019): 107662

A chemically contiguous hapten approach for a heroin-fentanyl vaccine.
Authors: Natori, Yoshihiro and Hwang, Candy S and Lin, Lucy and Smith, Lauren C and Zhou, Bin and Janda, Kim D
Journal: Beilstein journal of organic chemistry (2019): 1020-1031

Intravenous fentanyl use among people who inject drugs in Australia.
Authors: Geddes, Louise and Iversen, Jenny and Memedovic, Sonja and Maher, Lisa
Journal: Drug and alcohol review (2018): S314-S322

Combatting Synthetic Designer Opioids: A Conjugate Vaccine Ablates Lethal Doses of Fentanyl Class Drugs.
Authors: Bremer, Paul T and Kimishima, Atsushi and Schlosburg, Joel E and Zhou, Bin and Collins, Karen C and Janda, Kim D
Journal: Angewandte Chemie (International ed. in English) (2016): 3772-5