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Fentanyl-KLH conjugate

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Physical properties
Molecular weightN/A
SolventWater
Storage, safety and handling
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageFreeze (< -15 °C); Minimize light exposure
UNSPSC12171501
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Molecular weight
N/A
Small compounds (drugs or peptides) are not sufficiently complex by themselves to induce an immune response or be processed in a manner that elicits production of specific antibodies. For antibody production to be successful with small antigens, they must be chemically conjugated with immunogenic carrier proteins such as keyhole limpet hemocyanin (KLH). Adjuvants can be mixed and injected with an immunogen to increase the intensity of the immune response. Fentanyl-KLH conjugate is widely used for developing fentanyl antibodies, assays and tests. Our Fentanyl-KLH conjugate is highly purified to maximize its immunization responses.

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Citations


View all 1 citations: Citation Explorer
Rapid and Sensitive Detection of Fentanyl and Its Analogs by a Novel Chemiluminescence Immunoassay
Authors: Zhao, Jiang-yang and Uddin, Mezbah and Unsihuay, Daisy and Butler, William and Xia, Terrance W and Xu, Jayson Z and Wang, Simon and Sheng, Xiaolin and Jannetto, Paul J and Wang, Ping and others,
Journal: Clinical Chemistry (2024): hvae071

References


View all 46 references: Citation Explorer
A fentanyl vaccine constructed upon opsonizing antibodies specific for the Galα1-3Gal epitope.
Authors: Wang, Jiaxing and Ellis, Beverly and Zhou, Bin and Eubanks, Lisa M and Blake, Steven and Janda, Kim D
Journal: Chemical communications (Cambridge, England) (2020): 6551-6554
High Prevalence of Hepatitis C Infection Among Adult Patients at Four Urban Emergency Departments - Birmingham, Oakland, Baltimore, and Boston, 2015-2017.
Authors: Galbraith, James W and Anderson, Erik S and Hsieh, Yu-Hsiang and Franco, Ricardo A and Donnelly, John P and Rodgers, Joel B and Schechter-Perkins, Elissa M and Thompson, William W and Nelson, Noele P and Rothman, Richard E and White, Douglas A E
Journal: MMWR. Morbidity and mortality weekly report (2020): 569-574
Vaccine blunts fentanyl potency in male rhesus monkeys.
Authors: Tenney, Rebekah D and Blake, Steven and Bremer, Paul T and Zhou, Bin and Hwang, Candy S and Poklis, Justin L and Janda, Kim D and Banks, Matthew L
Journal: Neuropharmacology (2019): 107730
Monoclonal Antibodies for Combating Synthetic Opioid Intoxication.
Authors: Smith, Lauren C and Bremer, Paul T and Hwang, Candy S and Zhou, Bin and Ellis, Beverly and Hixon, Mark S and Janda, Kim D
Journal: Journal of the American Chemical Society (2019): 10489-10503
Psychopharmacology: neuroimmune signaling in psychiatric disease-developing vaccines against abused drugs using toll-like receptor agonists.
Authors: Yang, Fang and Kosten, Thomas R
Journal: Psychopharmacology (2019): 2899-2907
Rapid lateral flow assays based on the quantification of magnetic nanoparticle labels for multiplexed immunodetection of small molecules: application to the determination of drugs of abuse.
Authors: Guteneva, Natalia V and Znoyko, Sergey L and Orlov, Alexey V and Nikitin, Maxim P and Nikitin, Petr I
Journal: Mikrochimica acta (2019): 621
Development of vaccines to treat opioid use disorders and reduce incidence of overdose.
Authors: Pravetoni, Marco and Comer, Sandra D
Journal: Neuropharmacology (2019): 107662
A chemically contiguous hapten approach for a heroin-fentanyl vaccine.
Authors: Natori, Yoshihiro and Hwang, Candy S and Lin, Lucy and Smith, Lauren C and Zhou, Bin and Janda, Kim D
Journal: Beilstein journal of organic chemistry (2019): 1020-1031
Intravenous fentanyl use among people who inject drugs in Australia.
Authors: Geddes, Louise and Iversen, Jenny and Memedovic, Sonja and Maher, Lisa
Journal: Drug and alcohol review (2018): S314-S322
Functional and structural characterization of axonal opioid receptors as targets for analgesia.
Authors: Mambretti, Egle M and Kistner, Katrin and Mayer, Stefanie and Massotte, Dominique and Kieffer, Brigitte L and Hoffmann, Carsten and Reeh, Peter W and Brack, Alexander and Asan, Esther and Rittner, Heike L
Journal: Molecular pain (2016)