AAT Bioquest

Goat anti human IgG (Fc) serum

Ordering information
Catalog Number
Unit Size
Add to cart
Additional ordering information
InternationalSee distributors
Bulk requestInquire
Custom sizeInquire
ShippingStandard overnight for United States, inquire for international
Request quotation
Physical properties
Storage, safety and handling
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageRefrigerated (2-8 °C); Minimize light exposure


Anti-Human IgG (Fc specific) antiserum is produced in goat using purified human IgG, Fc fragment, as the immunogen. The antibody preparation is specific for human IgG, Fc fragment when tested against purified human IgA, IgG (Fc and Fab fragments). No reactivity is observed with the Fab fragment of human IgG, light chains, IgA, or IgM. The lack of interspecies cross reactivity with mouse or rat serum proteins makes this product excellent for the screening of human monoclonal antibodies produced by hybridoma cells grown in vivo in mouse or rat ascites fluids. This product has the ability to detect all human IgG subclasses in human biological fluids or tissues of normal or pathological situations such as cancer or autoimmune diseases. It is effective as a second antibody reagent in immunoassay procedures and can be used as starting material for conjugates using enzymes or fluorescent dyes. Anti-Human IgG (Fc specific) antibody produced in goat has been used in double-capture ELISA to measure antiglobulin responses in serum of transplant patients treated with CD52 monoclonal antibodies (CAMPATH-1G), detection of IgG levels rheumatoid arthritis patients, small intestine biopsies and patients with acute myocardial infarction by immunoblotting.


View all 50 references: Citation Explorer
Monoclonal secondary reagents do not outperform polyclonal secondary reagents for detection of anti-HLA IgG using single antigen flow beads assays.
Authors: Bonnet, Marie and Visentin, Jonathan and Caillat-Zucman, Sophie and Jollet, Isabelle and Taupin, And Jean-Luc
Journal: HLA (2020)
Immunoglobulin G-Encapsulated Gold Nanoclusters as Fluorescent Tags for Dot-Blot Immunoassays.
Authors: Zhuang, Quan-Quan and Deng, Hao-Hua and He, Shao-Bin and Peng, Hua-Ping and Lin, Zhen and Xia, Xing-Hua and Chen, Wei
Journal: ACS applied materials & interfaces (2019): 31729-31734
An infrared IgG immunoassay based on the use of a nanocomposite consisting of silica coated Fe3O4 superparticles.
Authors: Wang, Kexin and Ding, Yadan and Hong, Xia and Liu, Yichun
Journal: Mikrochimica acta (2019): 99
A rapid point-of-care test for dengue virus-1 based on a lateral flow assay with a near-infrared fluorescent dye.
Authors: Chen, Lin and Wang, Huagui and Guo, Tongsheng and Xiao, Chaohui and Liu, Licheng and Zhang, Xiaoguang and Liu, Bo and Li, Peiran and Liu, Aixia and Li, Bo and Li, Boan and Mao, Yuanli
Journal: Journal of immunological methods (2018): 23-27
Assembly of Multifunctionalized Gold Nanoparticles with Chemiluminescent, Catalytic, and Immune Activity for Label-Free Immunoassays.
Authors: Huang, Yao and Gao, Lingfeng and Cui, Hua
Journal: ACS applied materials & interfaces (2018): 17040-17046
A novel Time-resolved Fluoroimmunoassay for the quantitative detection of Antibodies against the Phospholipase A2 Receptor.
Authors: Huang, Biao and Wang, Liang and Zhang, Yi and Zhang, Jue and Zhang, Qiuhua and Xiao, Hualong and Zhou, Bin and Sun, Zhuxing and Cao, Ya-Nan and Chen, Yu and Hu, Zhigang and Sheng, Huiming
Journal: Scientific reports (2017): 46096
A New Enzyme-Linked Immunosorbent Assay for a Total Anti-T Lymphocyte Globulin Determination: Development, Analytical Validation, and Clinical Applications.
Authors: Montagna, Michela and La Nasa, Giorgio and Bernardo, Maria E and Piras, Eugenia and Avanzini, Maria A and Regazzi, Mario and Locatelli, Franco
Journal: Therapeutic drug monitoring (2017): 282-289
Simultaneous detection of platelet-specific antibodies based on a photonic crystal-encoded suspension array.
Authors: Kong, Xin and Ye, Baofen and Yang, Zixue and Chen, Baoan and Ling, Yun
Journal: Clinica chimica acta; international journal of clinical chemistry (2016): 72-7
Naked-eye sensitive ELISA-like assay based on gold-enhanced peroxidase-like immunogold activity.
Authors: Wang, Shasha and Chen, Zhaopeng and Choo, Jaebum and Chen, Lingxin
Journal: Analytical and bioanalytical chemistry (2016): 1015-22
Serum reactome induced by Bordetella pertussis infection and Pertussis vaccines: qualitative differences in serum antibody recognition patterns revealed by peptide microarray analysis.
Authors: Valentini, Davide and Ferrara, Giovanni and Advani, Reza and Hallander, Hans O and Maeurer, Markus J
Journal: BMC immunology (2015): 40