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iFluor® 450 Anti-human CD38 Antibody *HB7*

HB7 is an anti-human monoclonal antibody that recognizes the CD38 antigen. CD38 (alternatively called ADP-ribosyl cyclase or T10) is a 45 kD transmembrane glycoprotein that is expressed on the surface of cells such as B cells, dendritic cells and macrophages. CD38 is a component of critical cellular pathways, for instance, the apoptotic signaling pathway and B cell receptor signaling pathway. In addition, in many organisms, it is a repressor of bone resorption, is involved in the positive regulation of cell growth and is involved in the positive regulation of vasoconstriction. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands such as hyaluronic acid and CD16. CD38 is a moderately popular antibody target, with over 15000 publications in the last decade. CD38 is typically used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of immunology. This antibody was purified through affinity chromatography and conjugated to iFluor® 450 (ex/em = 451/502 nm). It is compatible with the 445 nm laser and 510/80 nm bandpass filter (for example, as in the BD FACSAria™ III).

Spectrum

Conjugation

We provide custom conjugation services for this antibody (eg. labeling of cd38 antibody with HRP). A list of available labels can be found in the table below:

AFAF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
ProteinsHRP, Alkaline Phosphatase, Streptavidin
TandemsAPC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small MoleculesBiotin
Traditional DyesFITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluorUV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page here.
Page updated on December 13, 2024

Ordering information

Price
Unit size
100 tests
500 tests
Catalog Number
1038204010382041
Quantity
Add to cart

Additional ordering information

Telephone1-800-990-8053
Fax1-800-609-2943
Emailsales@aatbio.com
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Purchase orderSend to sales@aatbio.com
ShippingStandard overnight for United States, inquire for international
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Antibody properties

Other namesADP-ribosyl cyclase; T10
CloneHB7
Hostmouse
IsotypeMouse IgG1, κ
Reactivityhuman
ApplicationFlow Cytometry (FACS); Fluorescence Imaging

Spectral properties

Correction Factor (260 nm)

0.45

Correction Factor (280 nm)

0.27

Extinction coefficient (cm -1 M -1)

400001

Excitation (nm)

451

Emission (nm)

502

Quantum yield

0.821

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
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