iFluor® 450 Anti-human CD38 Antibody *HB7*
HB7 is an anti-human monoclonal antibody that recognizes the CD38 antigen. CD38 (alternatively called ADP-ribosyl cyclase or T10) is a 45 kD transmembrane glycoprotein that is expressed on the surface of cells such as B cells, dendritic cells and macrophages. CD38 is a component of critical cellular pathways, for instance, the apoptotic signaling pathway and B cell receptor signaling pathway. In addition, in many organisms, it is a repressor of bone resorption, is involved in the positive regulation of cell growth and is involved in the positive regulation of vasoconstriction. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands such as hyaluronic acid and CD16. CD38 is a moderately popular antibody target, with over 15000 publications in the last decade. CD38 is typically used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of immunology. This antibody was purified through affinity chromatography and conjugated to iFluor® 450 (ex/em = 451/502 nm). It is compatible with the 445 nm laser and 510/80 nm bandpass filter (for example, as in the BD FACSAria™ III).
Spectrum
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Conjugation
We provide custom conjugation services for this antibody (eg. labeling of cd38 antibody with HRP). A list of available labels can be found in the table below:
For additional information about custom conjugations, please consult our services page here.
AF | AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750 |
Proteins | HRP, Alkaline Phosphatase, Streptavidin |
Tandems | APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5 |
Small Molecules | Biotin |
Traditional Dyes | FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5 |
iFluor | 350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7 |
mFluor | UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780 |
For additional information about custom conjugations, please consult our services page here.
Page updated on December 13, 2024