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iFluor® A7 Anti-human CD40 Antibody
G28.5
G28.5 is an anti-human monoclonal antibody that targets the CD40 antigen. CD40 (also known as Bp50) is a 48 kD transmembrane protein that is expressed on the surface of cells like macrophages, dendritic cells and stem cells. CD40 is a component of key cellular pathways, in particular, the tumor necrosis factor-mediated signaling pathway, immune response-regulating cell surface receptor signaling pathway and CD40 signaling pathway. Also, in many organisms, it upregulates interleukin-12 production, is a positive regulator of isotype switching to IgG isotypes and is a promoter of protein phosphorylation. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands like CD40L, CD154 and TRAP. CD40 is a very popular antibody target, with over 30000 publications in the last decade. CD40 is often used in flow cytometry applications as a phenotypic marker for differentiation of cell types, especially in the study of neuroscience. This antibody was purified through affinity chromatography and conjugated to iFluor® A7.
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CatalogSize
Price
Quantity
104010S0100 tests
Price
104010S1500 tests
Price
 
Antibody properties

Other namesBP50; TNFRSF5
CloneG28.5
Hostmouse
Isotypemouse igg1, κ
Reactivityhuman
ApplicationFlow Cytometry (FACS); Fluorescence Imaging
Spectral properties

Absorbance (nm)759
Correction factor (260 nm)0.03
Correction factor (280 nm)0.03
Extinction coefficient (cm -1 M -1)
275000
Excitation (nm)764
Emission (nm)782
Quantum yield
0.1
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
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Page updated on November 4, 2025