Name: Medetomidine KLH Conjugate
Brand: AAT Bioquest
SKU: 50656
Price: 969 USD
Availability: InStock

Medetomidine KLH Conjugate

Medetomidine KLH conjugate is a highly immunogenic conjugate of medetomidine coupled to keyhole limpet hemocyanin, optimized for robust antibody production against α2-adrenergic agonists in diagnostic applications.

High Immunogenicity: Utilizes KLH, a highly immunostimulatory protein ideal for eliciting strong T-cell dependent immune responses
Optimized Hapten-Carrier Design: Medetomidine is covalently conjugated to KLH to enhance immunogenicity and support robust antibody generation
Assay Development-Ready: Suitable for use as an immunogen in antibody production or as a coating antigen in ELISA and competitive immunoassays
Customizable Conjugation: Available with different hapten densities to meet specific immunization requirements

The chemical structure of Medetomidine KLH conjugate.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
50656	1 mg	Price

Overview

Medetomidine-KLH conjugate is a hapten-protein complex designed to facilitate the generation of anti-medetomidine antibodies and the development of immunoassays for detection and quantification of medetomidine. As a small-molecule α2-adrenergic agonist, medetomidine is non-immunogenic and requires conjugation to a carrier protein to elicit an adaptive immune response. In this construct, medetomidine is covalently linked to keyhole limpet hemocyanin (KLH), a high molecular weight, immunostimulatory protein frequently used in antibody production due to its strong T-cell dependent antigenicity. The conjugation process is optimized to maintain hapten integrity and maximize epitope availability, supporting high-affinity antibody generation. This reagent is well-suited for use in the development of polyclonal and monoclonal antibodies, as well as in competitive ELISA and other immunoanalytical assays. The conjugate is supplied in a lyophilized or buffered solution format to ensure stability and reproducibility. Custom conjugation formats, alternative carrier proteins, or specific hapten densities can be provided upon request to support specialized assay development or immunization protocols.

References

View all 50 references: Citation Explorer

Tailoring anaesthetic strategies for diabetes research: Acepromazine vs. medetomidine in Aachen minipigs.

Authors:

Soares, Sabrina and Wühl, Elisabeth and Schlund, Alexander and Schneider, Tobias and Sohns, Kyra and Rukwied, Roman and Schmelz, Martin and Kränzlin, Bettina

Journal:

PloS one (2025): e0316570

Comparison of intramuscular medetomidine versus medetomidine-vatinoxan sedation in bearded dragons (Pogonavitticeps).

Authors:

Pinho, Renata H and Reed, Maya and Chapman, Kelsey and Pang, Daniel Sj

Journal:

Veterinary anaesthesia and analgesia (2025): 72-77

An analysis of oxidative stress indices and clinical parameters in budgerigars (Melopsittacus undulatus) treated with medetomidine-ketamine and midazolam-ketamine.

Authors:

Amini, Zahra and Hoseinpour, Fatemeh and Ghashghaii, Ali and Cheraghi, Hadi

Journal:

Veterinary research forum : an international quarterly journal (2024): 237-242

A randomized clinical trial comparing the efficacy of lidocaine administered intravenously, intranasally or as infraorbital nerve block in dogs undergoing rostral rhinosocopy.

Authors:

Gomez-Martinez, Maria Isabel and Hughes, Jodie and Alderson, Briony and Deutsch, Julia

Journal:

Veterinary anaesthesia and analgesia (2024): 372-380

Postoperative opioid-free analgesia in dogs undergoing tibial plateau leveling osteotomy: a feasibility study.

Authors:

Didier, Caroline and Faucher, Sarah and Sarra Ferrer, Marti and Lapouge, Mathilde and Junot, Stéphane and Jourdan, Géraldine

Journal:

Frontiers in veterinary science (2024): 1394366

Physical properties

Solvent

DMSO

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure

Documents

Protocol
Safety Data Sheet
Certificate of Analysis

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Page updated on December 7, 2025