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PE/Texas Red® Anti-human CD11c Antibody
3.9
3.9 is an anti-human monoclonal antibody that forms an immune complex with the CD11c antigen. CD11c (sometimes called CR4 or ITGAX) is a 145 - 150 kD single-pass type I membrane protein that is expressed on the surface of cells such as macrophages, B cells and dendritic cells. In some organisms, CD11c promotes angiogenesis, positively regulates myelination and is a promoter of endothelial tube morphogenesis. Moreover, it is a component of essential cellular pathways, in particular, the cytokine-mediated signaling pathway and integrin-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands like ICAM-1 and 4 and fibrinogen. CD11c is a very popular antibody target, with over 26000 publications in the last decade. CD11c has been widely used in costimulatory molecules research, commonly serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to PE/Texas Red® (ex/em = 567/615 nm). It is compatible with the 561 nm laser and 610/20 nm bandpass filter (for example, as in the BD FACSAria™ Fusion).
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CatalogSize
Price
Quantity
101131S025 tests
Price
101131S1100 tests
Price
101131S2500 tests
Price
 
Antibody properties

Other namesIntegrin alpha-X; CR4; p150; ITGAX
Clone3.9
Hostmouse
IsotypeMouse IgG1, κ
Reactivityhuman
Spectral properties

Extinction coefficient (cm -1 M -1)
1960000
Excitation (nm)565
Emission (nm)613
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
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Page updated on October 25, 2025