Name: Purified Anti-human CD11b Antibody *ICRF44*
Brand: AAT Bioquest
SKU: 10112000
Price: 172 USD
Availability: InStock

Purified Anti-human CD11b Antibody

ICRF44

ICRF44 is an anti-human monoclonal antibody that forms an immune complex with the CD11b antigen. CD11b (also known as Mo1 or Mac-1) is a 165 - 170 kD transmembrane glycoprotein that is expressed on the surface of cells such as dendritic cells, macrophages, NK cells and T cells. In some organisms, CD11b is involved in the positive regulation of neuron death, is a promoter of hippocampal neuron apoptotic process and is a positive regulator of protein targeting to membrane. Furthermore, it has been thought to be involved with vital biological processes such as cell adhesion, specifically cell-cell adhesion via plasma-membrane adhesion molecules. CD11b is a member of vital cellular pathways, for example, the integrin-mediated signaling pathway, apoptotic signaling pathway and toll-like receptor 4 signaling pathway. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands like iC3b, ICAM-1, Factor X and 2. CD11b is a very popular antibody target, with over 45000 publications in the last decade. CD11b is frequently used in flow cytometry applications as a phenotypic marker for differentiation of cell types, especially in the study of innate immunity and immunology. This antibody was purified through affinity chromatography.

General packaging for catalog 10112000. Actual shipped packaging may vary.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
10112000	100 ug	Price

Conjugation

We provide custom conjugation services for this antibody (e.g. labeling of cd11b antibody with HRP). A list of available labels can be found in the table below:

Label Type	Available Labels
AF	AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
Proteins	HRP, Alkaline Phosphatase, Streptavidin
Tandems	APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small Molecules	Biotin
Traditional Dyes	FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor	350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluor	UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page

here

Physical properties

Molecular weight	N/A
Solvent	water

Antibody properties

Other names	CR3; Mac-1; Mo1; ITGAM; Integrin alpha-M
Clone	ICRF44
Host	mouse
Isotype	Mouse IgG1, κ
Reactivity	human
Application	Flow Cytometry (FACS); ELISA; IHC; Western Blot

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Refrigerated (2-8 °C); Minimize light exposure

Telephone
Fax
Email	sales@aatbio.com
International	See distributors
Bulk request	Inquire
Custom size	Inquire
Technical Support	Contact us
Request quotation	Request
Purchase order	Send to sales@aatbio.com
Shipping	Standard overnight for United States, inquire for international

Page updated on September 26, 2025