Purified Anti-human CD11c Antibody *3.9*
3.9 is an anti-human monoclonal antibody that forms an immune complex with the CD11c antigen. CD11c (sometimes called CR4 or ITGAX) is a 145 - 150 kD single-pass type I membrane protein that is expressed on the surface of cells such as macrophages, B cells and dendritic cells. In some organisms, CD11c promotes angiogenesis, positively regulates myelination and is a promoter of endothelial tube morphogenesis. Moreover, it is a component of essential cellular pathways, in particular, the cytokine-mediated signaling pathway and integrin-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands like ICAM-1 and 4 and fibrinogen. CD11c is a very popular antibody target, with over 26000 publications in the last decade. CD11c has been widely used in costimulatory molecules research, commonly serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography.
Conjugation
We provide custom conjugation services for this antibody (eg. labeling of cd11c antibody with HRP). A list of available labels can be found in the table below:
For additional information about custom conjugations, please consult our services page here.
AF | AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750 |
Proteins | HRP, Alkaline Phosphatase, Streptavidin |
Tandems | APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5 |
Small Molecules | Biotin |
Traditional Dyes | FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5 |
iFluor | 350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7 |
mFluor | UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780 |
For additional information about custom conjugations, please consult our services page here.
Page updated on October 14, 2024