AAT Bioquest

Purified Anti-human CD127 Antibody *A019D5*

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ShippingStandard overnight for United States, inquire for international
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Physical properties
Molecular weightN/A
Storage, safety and handling
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageRefrigerated (2-8 °C); Minimize light exposure


Other names
IL-7Rα; IL-7R
mouse IgG1
Flow Cytometry (FACS); ELISA; IHC; Western Blot
Molecular weight
A019D5 is an anti-human monoclonal antibody that targets the CD127 antigen. CD127 (sometimes called IL7R or IL-7Rα) is a 60 - 90 kD single-pass type i membrane protein that is located on the surface of cells such as stem cells and T cells. In some organisms, CD127 is an inhibitor of T cell mediated cytotoxicity, acts to positively regulate cell population proliferation and is an enhancer of gene expression. Also, it is involved with important cellular pathways, for instance, the cell surface receptor signaling pathway, interleukin-7-mediated signaling pathway and positive regulation of receptor signaling pathway via STAT. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands such as IL-7, PI3-kinase and CD132. CD127 is a fairly uncommon antibody target, with a little more than 7000 publications in the last decade. Even still, CD127 is commonly used in flow cytometry applications as a phenotypic marker for differentiation of cell types, especially in the study of immunology. This antibody was purified through affinity chromatography.

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We provide custom conjugation services for this antibody (eg. labeling of cd127 antibody with HRP). A list of available labels can be found in the table below:

AFAF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
ProteinsHRP, Alkaline Phosphatase, Streptavidin
TandemsAPC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small MoleculesBiotin
Traditional DyesFITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluorUV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page here.