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Purified Anti-human CD18 Antibody *HI18a*

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Telephone1-800-990-8053
Fax1-800-609-2943
Emailsales@aatbio.com
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ShippingStandard overnight for United States, inquire for international
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Storage, safety and handling
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

OverviewpdfSDSpdfProtocol


Other names
Integrin beta-2
Clone
HI18a
Host
mouse
Isotype
mouse IgG1
Reactivity
human
Application
Flow Cytometry (FACS); ELISA; IHC; Western Blot
HI18a is an anti-human monoclonal antibody that targets the CD18 antigen. CD18 (sometimes called Integrin beta-2, ITGB2 or beta 2) is a transmembrane glycoprotein that is found on the surface of cells like granulocytes, platelets, macrophages, dendritic cells and B cells. In many organisms, CD18 is an enhancer of neuron death, suppresses dopamine metabolic process and is a promoter of nitric oxide biosynthetic process. Additionally, it is involved with critical cellular pathways, for example, the integrin-mediated signaling pathway, cytokine-mediated signaling pathway and toll-like receptor 4 signaling pathway. CD18 has been associated with critical biological processes such as cell migration, particularly endothelial cell migration, and is associated with a variety of biologically interesting macromolecules/ligands, for example, CD11a, b and c. CD18 is a fairly uncommon antibody target, with a little more than 8300 publications in the last decade. Even still, CD18 is essential for signal transduction research, typically serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography.

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Conjugation


We provide custom conjugation services for this antibody (eg. labeling of cd18 antibody with HRP). A list of available labels can be found in the table below:

AFAF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
ProteinsHRP, Alkaline Phosphatase, Streptavidin
TandemsAPC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small MoleculesBiotin
Traditional DyesFITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluorUV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page here.