Purified Anti-human CD18 Antibody *HI18a*
HI18a is an anti-human monoclonal antibody that targets the CD18 antigen. CD18 (sometimes called Integrin beta-2, ITGB2 or beta 2) is a transmembrane glycoprotein that is found on the surface of cells like granulocytes, platelets, macrophages, dendritic cells and B cells. In many organisms, CD18 is an enhancer of neuron death, suppresses dopamine metabolic process and is a promoter of nitric oxide biosynthetic process. Additionally, it is involved with critical cellular pathways, for example, the integrin-mediated signaling pathway, cytokine-mediated signaling pathway and toll-like receptor 4 signaling pathway. CD18 has been associated with critical biological processes such as cell migration, particularly endothelial cell migration, and is associated with a variety of biologically interesting macromolecules/ligands, for example, CD11a, b and c. CD18 is a fairly uncommon antibody target, with a little more than 8300 publications in the last decade. Even still, CD18 is essential for signal transduction research, typically serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography.
Conjugation
We provide custom conjugation services for this antibody (eg. labeling of cd18 antibody with HRP). A list of available labels can be found in the table below:
For additional information about custom conjugations, please consult our services page here.
AF | AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750 |
Proteins | HRP, Alkaline Phosphatase, Streptavidin |
Tandems | APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5 |
Small Molecules | Biotin |
Traditional Dyes | FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5 |
iFluor | 350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7 |
mFluor | UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780 |
For additional information about custom conjugations, please consult our services page here.
Page updated on October 14, 2024