Purified Anti-human CD19 Antibody *HI19a*
HI19a is an anti-human monoclonal antibody that targets the CD19 antigen. CD19 (also known as T-cell surface antigen Leu-12 or B-lymphocyte surface antigen B4) is a 95 kD transmembrane glycoprotein that is found on the surface of cells like B cells and stem cells. CD19 plays a role in critical cellular pathways, in particular, the antigen receptor-mediated signaling pathway and B cell receptor signaling pathway. Furthermore, in certain organisms, it plays a role in the upregulation of phosphatidylinositol 3-kinase activity, positively regulates release of sequestered calcium ion into cytosol and plays a role in the upregulation of protein kinase B signaling. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands such as CD81 and Leu-13. CD19 is a very popular antibody target, with over 36000 publications in the last decade. CD19 is frequently used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of immunology and costimulatory molecules. This antibody was purified through affinity chromatography.
Conjugation
We provide custom conjugation services for this antibody (eg. labeling of cd19 antibody with HRP). A list of available labels can be found in the table below:
For additional information about custom conjugations, please consult our services page here.
AF | AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750 |
Proteins | HRP, Alkaline Phosphatase, Streptavidin |
Tandems | APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5 |
Small Molecules | Biotin |
Traditional Dyes | FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5 |
iFluor | 350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7 |
mFluor | UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780 |
For additional information about custom conjugations, please consult our services page here.
Page updated on October 12, 2024