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Purified Anti-human CD28 Antibody *CD28.2*

CD28.2 is an anti-human monoclonal antibody that forms an immune complex with the CD28 antigen. CD28 (sometimes called T44) is a 44 kD member of the Ig superfamily that is located on the surface of cells such as T cells. CD28 acts in essential cellular pathways, in particular, the cell surface receptor signaling pathway, T cell receptor signaling pathway and apoptotic signaling pathway. Furthermore, in some organisms, it positively regulates isotype switching to IgG isotypes, is an enhancer of interleukin-4 production and upregulates translation. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands such as PI3-kinase, CD80 and CD86. CD28 is a very popular antibody target, with over 30000 publications in the last decade. CD28 is essential for costimulatory molecules and immunology research, typically serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography.

Conjugation

We provide custom conjugation services for this antibody (eg. labeling of cd28 antibody with HRP). A list of available labels can be found in the table below:

AFAF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
ProteinsHRP, Alkaline Phosphatase, Streptavidin
TandemsAPC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small MoleculesBiotin
Traditional DyesFITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluorUV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page here.
Page updated on October 14, 2024

Ordering information

Price
Unit size
Catalog Number10280000
Quantity
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Additional ordering information

Telephone1-800-990-8053
Fax1-800-609-2943
Emailsales@aatbio.com
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Technical SupportContact us
Purchase orderSend to sales@aatbio.com
ShippingStandard overnight for United States, inquire for international
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Antibody properties

Other namesTp44; T44
CloneCD28.2
Hostmouse
Reactivityhuman
ApplicationFlow Cytometry (FACS); ELISA; IHC; Western Blot

Physical properties

Molecular weight

N/A

Solvent

water

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Refrigerated (2-8 °C); Minimize light exposure
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