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About
Purified Anti-human CD3 Antibody
HIT3b
The HIT3b monoclonal antibody binds to human CD3e, a 20 kD single-pass type i membrane protein commonly located on the surface of nkt cells, tregs, thymocytes (differentiation dependent)s, thymocytes and t cells. In many organisms, CD3 positively regulates T cell anergy, is a promoter of peptidyl-tyrosine phosphorylation and enhances interferon-gamma production. Also, it is a component of vital cellular pathways, namely, the G protein-coupled receptor signaling pathway, cell surface receptor signaling pathway and negative regulation of smoothened signaling pathway. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands such as TCR. CD3 is a very popular antibody target, with over 80000 publications in the last decade. CD3e is frequently used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of immunology. This antibody was purified through affinity chromatography.
| Catalog | Size | Price | Quantity |
|---|---|---|---|
| 10031000 | 100 ug | Price |
Antibody properties
| Other names | T3E |
| Clone | HIT3b |
| Host | mouse |
| Isotype | mouse IgG1 |
| Reactivity | human |
| Application | Flow Cytometry (FACS); ELISA; IHC; Western Blot |
Storage, safety and handling
| H-phrase | H303, H313, H333 |
| Hazard symbol | XN |
| Intended use | Research Use Only (RUO) |
| R-phrase | R20, R21, R22 |
Contact us
| Telephone | |
| Fax | |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Technical Support | Contact us |
| Request quotation | Request |
| Purchase order | Send to sales@aatbio.com |
| Shipping | Standard overnight for United States, inquire for international |
Page updated on October 24, 2025