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Purified Anti-human CD4 Antibody
RPA-T4
RPA-T4 is an anti-human monoclonal antibody that targets the CD4 antigen. CD4 (sometimes called T4 or Leu3a) is a 55 kD transmembrane glycoprotein that is expressed on the surface of cells such as granulocytes, T cells and macrophages. CD4 acts in vital cellular pathways, for instance, the T cell receptor signaling pathway, interleukin-15-mediated signaling pathway and enzyme linked receptor protein signaling pathway. Furthermore, in many organisms, it promotes interleukin-2 biosynthetic process, upregulates peptidyl-tyrosine phosphorylation and acts to positively regulate I-kappaB kinase/NF-kappaB signaling. CD4 has been associated with key biological processes such as membrane organization, specifically fusion of virus membrane with host plasma membrane, and is associated with a variety of biologically interesting macromolecules/ligands, namely, gp120 and Lck. CD4 is a very popular antibody target, with over 180000 publications in the last decade. CD4 is commonly used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of immunology. This antibody was purified through affinity chromatography.
General packaging for catalog 10041000. Actual shipped packaging may vary.
General packaging for catalog 10041000. Actual shipped packaging may vary.
CatalogSize
Price
Quantity
10041000100 ug
Price
 
Physical properties

Molecular weightN/A
Solventwater
Antibody properties

Other namesLeu-3; T4
CloneRPA-T4
Hostmouse
Isotypemouse IgG1
Reactivityhuman
ApplicationFlow Cytometry (FACS); ELISA; IHC; Western Blot
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageRefrigerated (2-8 °C); Minimize light exposure
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Page updated on September 26, 2025