Purified Anti-human CD40 Antibody *HI40a*
HI40a is an anti-human monoclonal antibody that targets the CD40 antigen. CD40 (alternatively called TNFRSF5) is a 48 kD transmembrane protein that is found on the surface of cells such as dendritic cells and epithelial cells. CD40 is a member of important cellular pathways, for instance, the tumor necrosis factor-mediated signaling pathway, immune response-regulating cell surface receptor signaling pathway and CD40 signaling pathway. Also, in many organisms, it upregulates GTPase activity, is a promoter of protein kinase C signaling and promotes transcription by RNA polymerase II. From a research standpoint, it is of biological interest due to its association with key macromolecules/ligands like TRAP and CD154. CD40 is a very popular antibody target, with over 30000 publications in the last decade. CD40 is commonly used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of cell biology and neuroscience. This antibody was purified through affinity chromatography.
Conjugation
We provide custom conjugation services for this antibody (eg. labeling of cd40 antibody with HRP). A list of available labels can be found in the table below:
For additional information about custom conjugations, please consult our services page here.
AF | AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750 |
Proteins | HRP, Alkaline Phosphatase, Streptavidin |
Tandems | APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5 |
Small Molecules | Biotin |
Traditional Dyes | FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5 |
iFluor | 350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7 |
mFluor | UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780 |
For additional information about custom conjugations, please consult our services page here.
Page updated on October 14, 2024