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Purified Anti-human CD40 Antibody *HI40a*

HI40a is an anti-human monoclonal antibody that targets the CD40 antigen. CD40 (alternatively called TNFRSF5) is a 48 kD transmembrane protein that is found on the surface of cells such as dendritic cells and epithelial cells. CD40 is a member of important cellular pathways, for instance, the tumor necrosis factor-mediated signaling pathway, immune response-regulating cell surface receptor signaling pathway and CD40 signaling pathway. Also, in many organisms, it upregulates GTPase activity, is a promoter of protein kinase C signaling and promotes transcription by RNA polymerase II. From a research standpoint, it is of biological interest due to its association with key macromolecules/ligands like TRAP and CD154. CD40 is a very popular antibody target, with over 30000 publications in the last decade. CD40 is commonly used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of cell biology and neuroscience. This antibody was purified through affinity chromatography.

Conjugation

We provide custom conjugation services for this antibody (eg. labeling of cd40 antibody with HRP). A list of available labels can be found in the table below:

AFAF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
ProteinsHRP, Alkaline Phosphatase, Streptavidin
TandemsAPC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small MoleculesBiotin
Traditional DyesFITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluorUV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page here.
Page updated on October 14, 2024

Ordering information

Price
Unit size
Catalog Number10400000
Quantity
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Additional ordering information

Telephone1-800-990-8053
Fax1-800-609-2943
Emailsales@aatbio.com
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Purchase orderSend to sales@aatbio.com
ShippingStandard overnight for United States, inquire for international
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Antibody properties

Other namesBP50; TNFRSF5
CloneHI40a
Hostmouse
Isotypemouse IgG2b
Reactivityhuman
ApplicationFlow Cytometry (FACS); ELISA; IHC; Western Blot

Physical properties

Molecular weight

N/A

Solvent

water

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Refrigerated (2-8 °C); Minimize light exposure
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