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Purified Anti-human CD45 Antibody
HI30
The HI30 monoclonal antibody recognizes human CD45, a 180 - 240 kD transmembrane glycoprotein typically found on the surface of B cells, neutrophils, hematopoietic cells and dendritic cells. CD45 is a component of vital cellular pathways, in particular, the regulation of receptor signaling pathway via JAK-STAT, B cell receptor signaling pathway and T cell receptor signaling pathway. Also, in certain organisms, it plays a role in the downregulation of cytokine-mediated signaling pathway, represses interleukin-2 biosynthetic process and is an enhancer of humoral immune response mediated by circulating immunoglobulin. CD45 has been thought to be involved with critical biological processes such as dephosphorylation, especially protein dephosphorylation, and is associated with a variety of biologically interesting macromolecules/ligands, for instance, p56lck. CD45 is a very popular antibody target, with over 50000 publications in the last decade. CD45 is often used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of neuroscience, immunology and neuroscience cell markers. This antibody was purified through affinity chromatography.
General packaging for catalog 10450000. Actual shipped packaging may vary.
General packaging for catalog 10450000. Actual shipped packaging may vary.
CatalogSize
Price
Quantity
10450000100 ug
Price
 
Physical properties

Molecular weightN/A
Solventwater
Antibody properties

Other namesLeukocyte Common Antigen (LCA); T200; PTPRC
CloneHI30
Hostmouse
Isotypemouse IgG1
Reactivityhuman
ApplicationFlow Cytometry (FACS); ELISA; IHC; Western Blot
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageRefrigerated (2-8 °C); Minimize light exposure
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Page updated on October 23, 2025