Purified Anti-human CD9 Antibody *HI9a*

HI9a is an anti-human monoclonal antibody that recognizes the CD9 antigen. CD9 (alternatively called MIC3, TSPAN29, Tetraspanin or 5H9 antigen) is a 24 kD member of the Tetraspan family that is expressed on the surface of cells like macrophages, granulocytes, epithelial cells, platelets and endothelial cells. In many organisms, CD9 is involved in the negative regulation of cellular component movement, represses cell population proliferation and negatively regulates platelet aggregation. From a research standpoint, it is of biological interest due to its association with critical macromolecules/ligands such as Integrin β1. CD9 is a fairly uncommon antibody target, with a little more than 6100 publications in the last decade. Even still, CD9 is frequently used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of immunology and stem cells. This antibody was purified through affinity chromatography.