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Purified Anti-human/mouse CD44 Antibody *IM7*

IM7 is an anti-human/mouse monoclonal antibody that targets the CD44 antigen. CD44 (sometimes referred to as Epican, H-CAM, PGP-1 or ECMR III) is a 85 kD glycoprotein that is found on the surface of cells like NK cells, endothelial cells and macrophages. CD44 is involved with key cellular pathways, in particular, the negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and interferon-gamma-mediated signaling pathway. Moreover, in some organisms, it upregulates peptidyl-tyrosine phosphorylation, plays a role in the upregulation of ERK1 and ERK2 cascade and is a positive regulator of peptidyl-serine phosphorylation. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands like MIP1β, Ankyrin, Collagen and Osteopontin. CD44 is a very popular antibody target, with over 40000 publications in the last decade. CD44 is vital to cell adhesion, cell biology and immunology research, often serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography.

Conjugation

We provide custom conjugation services for this antibody (eg. labeling of cd44 antibody with HRP). A list of available labels can be found in the table below:

AFAF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
ProteinsHRP, Alkaline Phosphatase, Streptavidin
TandemsAPC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small MoleculesBiotin
Traditional DyesFITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluorUV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page here.
Page updated on October 12, 2024

Ordering information

Price
Unit size
Catalog Number10441000
Quantity
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Additional ordering information

Telephone1-800-990-8053
Fax1-800-609-2943
Emailsales@aatbio.com
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Custom sizeInquire
Technical SupportContact us
Purchase orderSend to sales@aatbio.com
ShippingStandard overnight for United States, inquire for international
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Antibody properties

Other namesECMR-III; Pgp-1; HUTCH-1; H-CAM
CloneIM7
Hostrat
Reactivityhuman; mouse
ApplicationFlow Cytometry (FACS); ELISA; IHC; Western Blot

Physical properties

Molecular weight

N/A

Solvent

water

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Refrigerated (2-8 °C); Minimize light exposure
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