Purified Mouse Anti-human IgA Antibody *AD3, monoclonal*

Immunoglobulin heavy constant α 1 (also known as Ig α-1 chain C region TRO, Ig α-1 chain C region BUR or Ig α-1 chain C region) is a protein with a molecular weight of 44 kDa, located in the external side of plasma membrane, immunoglobulin complex, circulating and extracellular exosome of cells. Sequencing of Ig α-1 chain C region BUR has shown it contains 3 conserved structural units: Ig-like 1, Ig-like 2 and Ig-like 3 domain. It recognizes antigen. Ig α-1 chain C region BUR is the subject of comprehensive study stemming from the fact that it plays a role in the B cell receptor signaling pathway and complement activation, classical pathway. It is an integral part of organismal processes, for instance, retina homeostasis, leukocyte migration and antibacterial humoral response. It is an enhancer of respiratory burst and B cell activation.