Purified Mouse Anti-human/mouse FoxP3 Antibody *3G3, monoclonal*
Ordering information
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Additional ordering information
Telephone | 1-800-990-8053 |
Fax | 1-800-609-2943 |
sales@aatbio.com | |
International | See distributors |
Bulk request | Inquire |
Custom size | Inquire |
Shipping | Standard overnight for United States, inquire for international |
Storage, safety and handling
Intended use | Research Use Only (RUO) |
Overview | Protocol |
See also: Antibodies and Proteomics
Other names | Clone 3G3 | Host mouse | Reactivity human; mouse | Application FC (QC TESTED); WB |
Forkhead box protein P3 is a 47 kDa protein that can be found in the nuclear chromatin, cytoplasm and nucleoplasm of cells. In Homo sapiens, forkhead box protein P3 is the subject of intensive application due to the fact that it is a component of the T cell receptor signaling pathway and regulation of Wnt signaling pathway. Forkhead box protein P3 is a promoter of peripheral T cell tolerance induction, histone acetylation and DNA-templated transcription, on the other hand, also negatively regulates interleukin-17 production, interleukin-4 production and activated T cell proliferation. It is an integral part of DNA-templated transcription, isotype switching to IgG isotypes and T cell anergy, and also, binds to Fork-head and sequence-specific DNA. Forkhead box protein P3 has been associated with key functions like protein homodimerization, DNA-binding transcription factor and transcription corepressor activity, and furthermore, plays an important role in organismal processes, for instance, T cell mediated immunity, T cell activation and response to virus. Forkhead box protein P3 is clinically significant because abnormalities in its function have been thought to be involved with diseases such as Immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX). Immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome- , a x-linked recessive inheritancedisorder characterized by Diabetes mellitus, Immune dysregulation and Eosinophilia- has especially been of interest to researchers.
Conjugation
We provide custom conjugation services for this antibody (eg. labeling of FoxP3 antibody with HRP). A list of available labels can be found in the table below:
For additional information about custom conjugations, please consult our services page here.
AF | AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750 |
Proteins | HRP, Alkaline Phosphatase, Streptavidin |
Tandems | APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5 |
Small Molecules | Biotin |
Traditional Dyes | FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5 |
iFluor | 350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7 |
mFluor | UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780 |
For additional information about custom conjugations, please consult our services page here.
Application notes
A Meta-Analysis of Common Calcium Indicators
A New Protein Crosslinking Method for Labeling and Modifying Antibodies
A Novel Fluorescent Probe for Imaging and Detecting Hydroxyl Radical in Living Cells
A Novel NO Wash Probeniceid-Free Calcium Assay for Functional Analysis of GPCR and Calcium Channel Targets
Abbreviation of Common Chemical Compounds Related to Peptides
A New Protein Crosslinking Method for Labeling and Modifying Antibodies
A Novel Fluorescent Probe for Imaging and Detecting Hydroxyl Radical in Living Cells
A Novel NO Wash Probeniceid-Free Calcium Assay for Functional Analysis of GPCR and Calcium Channel Targets
Abbreviation of Common Chemical Compounds Related to Peptides