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AAT Bioquest

Purified Mouse Anti-human/mouse/rat α/β-Tubulin dimer Antibody *TU-10, monoclonal*

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Telephone1-800-990-8053
Fax1-800-609-2943
Emailsales@aatbio.com
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Intended useResearch Use Only (RUO)

OverviewpdfSDSpdfProtocol


Other names
Clone
TU-10
Host
mouse
Reactivity
human; mouse; rat; pig; non-human primates
Application
WB; ICC
Tubulin α-4A chain (sometimes referred to as Tubulin α-1 chain, Tubulin H2-α, Testis-specific α-tubulin or α-tubulin 1) is a protein with a molecular weight of 58 kDa, located in the cytoplasm and extracellular exosome of cells. In humans, tubulin α-4A chain has been closely linked to important functions such as GTPase activity. It aids in G2/M transition of mitotic cell cycle. It binds to GTP and protein kinase. It is thought to be essential to organismal processes, for instance, microtubule cytoskeleton organization, ciliary basal body-plasma membrane docking and G2/M transition of mitotic cell cycle. Mutations and abnormalities in tubulin α-4A chain have been closely linked to a number of diseases, for instance, amyotrophic lateral sclerosis 22, with or without frontotemporal dementia (ALS22). Amyotrophic lateral sclerosis 22, with or without frontotemporal dementia, an autosomal dominant inheritancedisorder characterized by amyotrophic lateral sclerosis and frontotemporal dementia, has in particular been of interest to researchers.

Conjugation


We provide custom conjugation services for this antibody (eg. labeling of α/β-Tubulin dimer antibody with HRP). A list of available labels can be found in the table below:

AFAF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
ProteinsHRP, Alkaline Phosphatase, Streptavidin
TandemsAPC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small MoleculesBiotin
Traditional DyesFITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluorUV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page here.